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The Dr. Gabrielle Lyon Show

You Can Reverse Aging with Muscle | Kevin Murach PhD

The Dr. Gabrielle Lyon Show

Dr. Gabrielle Lyon

Medicine, Science, Health & Fitness, Life Sciences

4.6911 Ratings

🗓️ 9 January 2024

⏱️ 89 minutes

🧾️ Download transcript

Summary

Kevin A. Murach, Ph.D., completed a master’s degree in Exercise Physiology at James Madison University in Harrisonburg, Virginia, then earned his Ph.D. in Human Bioenergetics from the Ball State Human Performance Laboratory in Muncie, Indiana. After Ball State, Dr. Murach spent six years as a post-doctoral fellow/scholar studying muscle stem cells at the University of Kentucky Center for Muscle Biology in Lexington under the guidance of Drs. Charlotte Peterson and John McCarthy. He now is an Assistant Professor at the University of Arkansas. His current research uses human muscle samples, primary cell culture and genetically modified mouse models to understand the molecular cues that drive exercise adaptations and aging, and the interaction between the two.

In this episode we discuss:

  • Why Yamanaka factors matter for muscle adaptation and age reversal.
  • How does exercise improve longevity?
  • What is DNA methylation and how does it affect muscle?
  • How to train for overall health and aging.

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Transcript

Click on a timestamp to play from that location

0:00.0

Welcome to the Dr. Gabriel Lion Show, where I believe a healthy world is based on transparent

0:08.5

conversations.

0:14.4

In today's episode of the Dr. Gabrielle Lion Show, I sit down with Kevin Murak, PhD. He received a master's degree in

0:24.4

exercise physiology at James Madison University in Virginia. He then earned his PhD in human

0:33.0

bioenergetics from the Ball State Human Performance Laboratory in Indiana.

0:39.0

His dissertation, which we talk about in this episode, was a collaboration with NASA

0:45.1

aimed at optimizing the exercise prescription for astronauts on the International Space Station.

0:53.1

After Ball State, he spent six years as a postdoctoral fellow and scholar studying one of my

0:59.0

favorite topics, muscle stem cells at the University of Kentucky's Center for Muscle Biology

1:05.4

in Lexington.

1:07.0

He is now an assistant professor at the University of Arkansas.

1:30.8

He has a lab. It's called M3R, which stands for muscle mass regulation. What I love about this conversation is it really highlights the basic science. We talk about nutrition. We talk about exercise. Kevin does so well is examine some of the genetic and epigenetic expressions of what exercise does. We spoke about the Yamanaka factor. These are the

1:38.8

factors that we think about from an age reversal and quote regeneration perspective. We also discuss what is DNA

1:47.9

methylation? We're hearing a lot about methylation and how does that relate to the aging

1:53.0

and adaptation of skeletal muscle. And finally, how does exercise improve longevity from a genetic and epigenetic expression?

2:04.3

I hope you love this episode.

2:06.0

As always, we provide this content free.

2:08.9

It would mean the world to me.

2:10.6

And our team, if you share it, leave us a review.

2:14.8

We would love your feedback.

2:16.8

Our goal is to educate. Let's dive in to this

2:21.1

episode. Thank you to Aquatru for sponsoring this episode of the show. Having clean,

...

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