Why Your Body Does Not Want You to Lose Weight
American Glutton
American Glutton
4.9 • 3K Ratings
🗓️ 16 February 2026
⏱️ 58 minutes
🧾️ Download transcript
Summary
What does it really take to lose weight and keep it off for good? Ethan sits down with Dr. Holly Wyatt to unpack the science of metabolism, appetite regulation, and long term weight management. They explore why the body resists weight loss, how biology influences hunger, and what actually works beyond willpower. Dr. Wyatt shares practical insights drawn from decades of clinical research, offering clarity in a space full of confusion.
If you are serious about understanding sustainable fat loss, this conversation delivers real answers.
For more insights and updates from Ethan, sign up for his newsletter at https://ethansuplee.substack.com/subscribe.
SHOW HIGHLIGHTS
00:00:00 Welcome, Dr. Holly Wyatt
00:02:09 Ethan’s Weight Loss History
00:04:32 Appetite and Hormones Explained
00:12:31 The Reality of Weight Loss Maintenance
00:13:57 Extreme Calorie Restriction
00:16:37 Why We Regain Weight
00:18:28 Metabolism Adaptation
00:30:45 Set Point and Biological Defense
00:40:26 Exercise and Long-Term Health
00:50:34 Final Takeaways on Sustainable Fat Loss
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Transcript
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| 0:00.0 | I want to take one minute and talk to you about three things. The first is Substack. I'm on Substack. |
| 0:06.7 | I'm writing longer form things and I'm having incredible conversations with my subscribers. So check it out. |
| 0:12.4 | Go to EthanSupple.com and join in on the conversation. We want your voice heard there too. |
| 0:20.4 | That's one. |
| 0:21.4 | The second thing is the prep deck. |
| 0:22.8 | Do you have your prep deck? |
| 0:24.5 | The prep deck is an incredible tool |
| 0:26.6 | that takes the guesswork out of meal planning. |
| 0:29.1 | I have diet fatigue. |
| 0:30.4 | My wife has diet fatigue. |
| 0:32.2 | We go to the prep deck and we allow the deck |
| 0:34.5 | to choose what we eat for us. |
| 0:36.6 | It's a wonderful resources. |
| 0:39.0 | So if you don't have one, grab yours today. |
| 0:41.3 | And finally, American Glutton has protein powder. |
| 0:45.8 | You can get a 25 gram dose of protein throughout the day in delicious chocolate and vanilla flavors. |
| 0:52.6 | So go to Americanglutton.net and get your protein powder today. |
| 0:57.9 | Hi, I'm Ethan Soply. |
| 1:00.1 | Welcome to American Glutton. |
| 1:02.0 | Outside of acting, my two favorite things to do are diet and eat. |
| 1:05.9 | I have a very complicated relationship with food, |
| 1:08.3 | and on this podcast, we're going to talk about all of it. |
... |
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