What is ibogaine, and why is it in the news?
Science Friday
Science Friday and WNYC Studios
4.4 • 6.3K Ratings
🗓️ 29 April 2026
⏱️ 19 minutes
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| 0:00.0 | Hey, it's Flora, and you are listening to Science Friday. |
| 0:07.4 | Psychedelic news from the Oval Office. |
| 0:10.2 | If these turn out to be as good as people are saying, it's going to have a tremendous impact on this country and other countries too. |
| 0:17.7 | This month, Joe Rogan and RFK Jr. stood behind President Trump as he announced |
| 0:22.4 | his administration would set aside funding and loosen the bureaucratic process at the FDA to |
| 0:28.3 | fast-track psychedelic therapy research. Joe Rogan named-checked one drug in particular, Ibogaine. |
| 0:37.2 | Rogan said he sent Trump information about Ibegain's potential promise for addiction, and Trump replied. |
| 0:42.4 | The text message came back, sounds great. |
| 0:45.9 | Do you want FDA approval? |
| 0:47.4 | Let's do it. |
| 0:48.7 | It was literally that quick. |
| 0:51.2 | So Ibegain comes from the root bark of the Iboga plant found in Central Africa, |
| 0:56.7 | and it has psychedelic properties. And besides its potential for curbing opioid addiction, veterans in |
| 1:03.0 | the U.S. have been advocates for this treatment because it's shown some promise for treating PTSD and |
| 1:08.4 | other conditions. But it also can be risky to take, especially if you have |
| 1:12.1 | heart issues. Now, if you have never heard of the drug Ibogaine, you're not alone, compared to |
| 1:18.5 | other hallucinogenic drugs like psilocybin or ketamine, Ibogaine has not made it to the medical |
| 1:24.9 | mainstream yet. So what is the story with this drug? Here to tell us about |
| 1:29.5 | its history is neuroscientist and pharmacologist Dr. Deborah Mash, who's been studying Ibegain since |
| 1:34.8 | the 90s, maybe as long as any scientist in the U.S. For full transparency, she's also the founder |
| 1:40.6 | and CEO of a company that's developing a therapeutic drug based off of Ibegain. |
| 1:46.1 | And here to tell us how Ibegain fits in with this growing interest in medical psychedelics, |
... |
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