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Police Off The Cuff/Real Crime Stories

Unsealed The Pattern Behind Nancy Guthrie's Disappearance.

Police Off The Cuff/Real Crime Stories

Bill Cannon Police off the Cuff/Real Crime Stories

Law Enforcement, Crime, True Crime, Military

4.4870 Ratings

🗓️ 2 May 2026

⏱️ 9 minutes

🧾️ Download transcript

Summary

There’s another major angle tonight, and that comes from former FBI profiler Jim Clemente. Clemente has publicly said the blood evidence at Nancy Guthrie’s front door may point to a single abductor. That is not a formal law-enforcement conclusion, but it is a serious opinion from someone who knows how to read offender behavior and scene dynamics. And if he’s right, then investigators may be looking at one offender, not a team, someone confident enough to approach the home alone, control an elderly victim, and get out without immediate detection.

Transcript

Click on a timestamp to play from that location

0:00.0

You know, it's hard to predict since we don't really know what's going on in the inside,

0:03.6

but based on what we know at the moment, this is what I'm most hopeful about,

0:08.0

because it will be a single source DNA profile as opposed to the complex mixture that they've been trying to work with.

0:16.0

You know, very interesting because I just want to mention that in the Gilgo Beach serial killer case,

0:23.5

where Rex Eweiman, the Gilgo Beach serial killer, we can say that now since he's pled guilty,

0:31.4

a case from 1993 was solved by a hair on the back of the victim.

0:39.5

Her name was Sandra Castilla.

0:41.9

That hair, using the technology that C.C. Moore is talking about right now,

0:49.2

that hair came back to Rex Ullman.

0:53.1

But when it first occurred in 1993, the technology did not exist

0:59.6

yet to identify that hair, but it does now. So that was one of the first, though, the earliest

1:06.5

cases where the single hair, rootless hair, was used to identify a perpetrator.

1:15.8

So in this case, that's what they're also hoping on, because early on they also had

1:22.0

what they referred to as co-mingled DNA. That's DNA that is mingled with another person or person's DNA. So is it possible

1:34.7

for the DNA lab to separate this DNA and to get profiles or a profile of the perpetrator

1:42.8

through unmingling the co-mingled DNA.

1:46.6

And the answer to that is yes, there is a technology to do that also.

1:53.0

So all of this science, and we've said early on in this case, that if anything is going to solve this case, it's going to be science.

2:04.1

Science is absolutely going to solve this case.

2:07.6

And you see the little thumbnail up on the screen, co-mingled DNA evidence.

2:12.9

And there is a possibility that they can identify co-mingled DNA. And, you know, C.C. Moore has said on

2:21.7

a couple shows that she believes that they should go back again into the house, into Nancy Guthrie's

...

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