TWiV 997: Inside Omicron with Mohsan Saeed

This Week in Virology

Vincent Racaniello

Vincent, Microbe, Medicine, Microbiology, Racaniello, Infection, Virus, Virology, Pathogen, Infectious, Twiv, Science & Medicine

4.8 • 2.2K Ratings

🗓️ 2 April 2023

⏱️ 115 minutes

🔗️ Recording | iTunes | RSS

🧾️ Download transcript

Summary

Mohsan joins TWiV to discuss the work of his laboratory showing that spike and nsp6 are determinants of Omicron attenuation, and why the work was widely misinterpreted by the press and the public. Hosts: Vincent Racaniello, Alan Dove, and Rich Condit Guest: Mohsan Saeed Subscribe (free): Apple Podcasts, Google Podcasts, RSS, email Become a patron of TWiV! Links for this episode •Register for ASV 2023 •MicrobeTV Discord Server • Spike and nsp6 determinants of Omicron attenuation (Nature) •China releases genomic data from Wuhan market (Science) •Timestamps by Jolene. Thanks! Weekly Picks Rich – For pianist Dan Tepfer, improvisation is the mother of Bach’s Inventions Alan – HMS Victory 3D animated tour Vincent – The Fight Over Penn Station and Madison Square Garden Listener Picks Douglas – How’s Your City Doing? Ask the Honeybees. Intro music is by Ronald Jenkees Send your virology questions and comments to [email protected]

Transcript

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0:00.0	This week in virology, the podcast about viruses, the kind that make you sick.
0:10.4	From micro TV, this is twiv this week in virology episode 997 recorded on March 31st,
0:20.6	2023. I'm Vincent Racken Yellow and you're listening to the podcast all about viruses.
0:28.6	Joining me today from Austin, Texas, rich, condit. Hello there, Vincent. We have
0:36.1	81 degrees Fahrenheit, sunny, windy, all good. Here in New York City, it's 10 degrees,
0:43.3	Celsius, and windy also. It's still cold. The overnight at freezes here still. The bird
0:50.4	baths are frozen in the morning, also joining us from Western Massachusetts, Alan Dove.
0:57.3	Good to be here. It's 45 Fahrenheit, seven Celsius, and it just, it's gone overcast today,
1:04.6	and we're supposed to get rain into Saturday. So kind of typical getting into mud season here
1:10.2	in Western mass. 997, we are three episodes away from 1,000. I think I have a few seats left,
1:19.2	folks. We had some cancellations. So if you're interested, you could still get in. You send me an
1:25.6	email, Vincent at microbe.tv, and I'll send you the details. Yeah, a few people cancelled,
1:32.9	which is too bad for them. They're going to miss out. Our guest today is from Boston University
1:41.1	School of Medicine, Moson Saeed. Welcome to Twiv. Thank you for having me, Vincent. Here in Boston,
1:49.1	it is seven degrees centigrade, and it is partly cloudy. I think it's going to rain
1:54.6	soon, probably from 6 p.m. You'll get my weather about an hour later. It's the only thing that
1:59.4	happens first in Western mass and later in Boston. Moson is sitting. Are you in the same building as
2:06.1	the needle? Is that where you are? Exactly. So this is national emerging infectious diseases laboratories
2:14.1	called needle. Should we call it needle, but people call it needle.
2:18.0	I think that's because of our episode title, episode 200, threading the needle, and it's forever
2:24.9	going to be the needle after that. Oh, so what was that? How many years ago? Let's see. I just
2:31.2	looked it up. Twiv 200. That was September 23rd, 2012. It was me. 10 years ago,
	...

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