TWiV 995: Viral origin stories

This Week in Virology

Vincent Racaniello

Vincent, Microbe, Medicine, Microbiology, Racaniello, Infection, Virus, Virology, Pathogen, Infectious, Twiv, Science & Medicine

4.8 • 2.2K Ratings

🗓️ 26 March 2023

⏱️ 123 minutes

🔗️ Recording | iTunes | RSS

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Summary

TWiV discusses genetic evidence of susceptible wildlife in SARS-CoV-2 positive samples at the Huanan Wholesale Seafood Market, polio cases in African linked to a new polio vaccine that was designed to not cause the disease, and structural conservation of hepatitis B virus capsid proteins over millions of years despite a shift from a naked to an enveloped capsid. Click arrow to play Download TWiV 995 (74 MB .mp3, 123 min) Subscribe (free): Apple Podcasts, Google Podcasts, RSS, email Become a patron of TWiV! Links for this episode •Register for ASV 2023 •MicrobeTV Discord Server • More evidence for SARS-CoV-2 spillover (Zenodo) •Polio cases linked to nOPV2 (Science; GPEI statement) •nOPV2 on TWiV 756 •Engineering OPV to prevent reversion to neurovirulence (Cell Host Microbe) •Stability of nOPV2 in children (npj Vaccines) •2A changes compensate for 5′-UTR disruptions (Virology) •HBV shifts from naked to enveloped (Nat Comm) •Letters read on TWiV 995 •Timestamps by Jolene. Thanks! Weekly Picks Dickson – Jazz Project: Bass: Ray Brown, Ron Carter, Percy Heath Angela – The nervous system may play a role in severe allergic reactions through immune cell (mast cells) cross-talk with neurons Brianne – Science Museums Take Stock of 1.1 Billion Objects from Around the World Vincent – Architect Breaks Down 5 of the Most Common Skyscraper Styles In New York Listener Picks Gary – Tony Fauci on PBS Stefanie – What Do You Find Beautiful about Viruses? A Post-COVID Assessment Strategy Intro music is by Ronald Jenkees Send your virology questions and comments to [email protected]

Transcript

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0:00.0	This week in virology, the podcast about viruses, the kind that make you sick.
0:10.5	From micro TV, this is TWIV, this week in virology episode 995 recorded on March 24th,
0:20.8	2023. I'm Vincent Racken Yellow, and you're listening to the podcast all about viruses.
0:28.0	Joining me today here at the incubator in New York City, Thixandipomeye. Hello, Vincent,
0:34.4	and everybody. I don't want you to say hello again. No, we're not going to do it again.
0:40.8	Welcome back to the incubators. Thank you again. Also joining us from Madison, New Jersey,
0:46.8	Brianna Barker. Hi, great to see you. And it's 10 degrees Celsius here, by the way. Yes, but you never
0:53.4	know it inside. It's very comfortable. What is it like in Drew? It is. I have 52 Fahrenheit,
0:59.8	so that would be about 11 Celsius. 32. In Madison, it's nice. And also joining us from Montreal,
1:05.9	Canada, Angela Mingarali. Hello, how's everyone doing? Here, I have to say, it's the cold. This is
1:13.1	39 Fahrenheit or four degrees Celsius. So, but for us, it's a beautiful day. It's partially cloudy.
1:21.2	And when the sun comes out, it is very much appreciated as our winter has been very long.
1:28.1	Yes, but in the summer, it gets very hot there also. Yeah, Montreal is a very extreme climate. We can
1:33.2	go from, I'm going to talk in Celsius, but plus 40 to minus 40. So the delta is almost 80 degrees.
1:40.9	Really? Yeah. That's very hot. That's hot. And very humid. Can I have an ASV there in a couple of
1:46.8	years, right? Yeah. Yeah. I think it's 2026, isn't it? I hope it's not plus 40. It might be,
1:56.6	but you'll be done with your PhD by then, right? Hopefully. It's the fly. It'll be somewhere else.
2:02.4	Hopefully. What are you going to do after your PhD? Do you know you're going to get another degree?
2:06.2	No, no, I have enough degrees. I think I'll have all the degrees I need. I'm not sure yet. I don't
2:12.4	think I want to open my own lab, but I really enjoy teaching. So
2:18.5	something teaching adjacent. I also enjoy science communication. So we'll see.
2:25.2	We have a PSA about eight, speaking of ASV. There's one this year. It's in Athens, Georgia, June 24th
	...

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