TWiV 945: Clinical update with Dr. Daniel Griffin

This Week in Virology

Vincent Racaniello

Vincent, Microbe, Medicine, Microbiology, Racaniello, Infection, Virus, Virology, Pathogen, Infectious, Twiv, Science & Medicine

4.8 • 2.2K Ratings

🗓️ 15 October 2022

⏱️ 44 minutes

🔗️ Recording | iTunes | RSS

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Summary

In his weekly clinical update Dr. Griffin discusses a healthcare-associated infection with Monkeypox virus, air and surface sampling for monkeypox virus in a UK hospital, misrepresentation and nonadherence regarding COVID19 public health measures, tolerability and immunogenicity of an intranasally-administered adenovirus-vectored COVID-19 vaccine, clinical, virologic, and immunologic evaluation of symptomatic rebound following Nirmatrelvir/Ritonavir treatment, early outpatient treatment with Eemdesivir in patients at high risk for severe COVID-19, Molnupiravir plus usual care versus usual care alone as early treatment for adults with COVID-19 at increased risk of adverse outcomes, and outcomes among confirmed cases and a matched comparison group in the long-COVID in Scotland. Subscribe (free): Apple Podcasts, Google Podcasts, RSS, email Become a patron of TWiV! Links for this episode Research assistant position with Amy Rosenfeld (pdf) Support MicrobeTV with a Spike t-shirt at Vaccinated.US A healthcare-associated infection with monkeypox virus (OFID) Air and surface sampling for monkeypox virus (The Lancet) Misrepresentation & nonadherence in COVID-19 public health measures (JAMA) Tolerability and immunogenicity of a COVID-19 vaccine (The Lancet) PAXLOVID patient eligibility screening checklist (FDA) Evaluation of symptomatic disease rebound following PAXLOVID (CID) Outpatient treatment with Remdesivir in patients at high risk (OFID) Remdesivir fact sheet for providers (Veklury) Bebtelovimab fact sheet for providers (FDA) Molnupiravir as early treatment for adults with COVID-19 (SSRN) Outcomes among confirmed cases and matched comparison group in long-COVID (Nature) Dr. Griffin’s treatment guide (pdf) Contribute to Floating Doctors fundraiser at PWB Letters read on TWiV 945 Timestamps by Jolene. Thanks! Intro music is by Ronald Jenkees Send your questions for Dr. Griffin to [email protected]

Transcript

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0:00.0	This week in virology, the podcast about viruses, the kind that make you sick.
0:10.5	From micro TV, this is Twiv this week in virology episode 945 recorded October 13th, 2022.
0:22.1	I'm Vincent Drakenyllo and you're listening to the podcast all about viruses. Joining me today from
0:28.5	New York, Daniel Griffin. Hello, everyone. Before I hand it over to you, Daniel, two quick
0:34.9	announcements. First, the laboratory of Amy Rosenfeld, which is at Seiber in the FDA,
0:41.7	is looking for research assistant. Now Amy was my last trainee. She moved the entire project set
0:47.5	of a lab down to the FDA and she's working on it there, including the unexpected observation
0:53.9	that there are antibodies that can cross-react among enteroviruses. So the research assistant will
0:58.8	help figure out what that means, both in cell culture and in animal models, which you'll help to
1:04.5	develop. And all the work will be done at BSL2 levels. If you want more information, you can send
1:12.0	Amy and email Amy. Rosenfeld at FDA.hhs.gov or in the show notes, we'll have a link to a PDF document
1:22.2	with more details. And also show your support for what we do here at microobtv by buying a spike
1:29.5	t-shirt from vaccinated.us. Go over there and pick your t-shirt, put it in the cart. And when you
1:35.3	check out, use the promo code microobtv and they will send their profits to us to help support
1:42.4	our work in science communication. Thanks to Matt and vaccinated us for their support.
1:47.6	All right, Vincent, they need to make collar shirts so I can wear the spike shirt with my bowtie.
1:53.2	It's a great idea. And by the way, I know someone who will buy spike bowties if you make them.
1:59.2	All right, let's get right into it. Anyone who stops learning is old, whether at 20 or 80.
2:05.9	Anyone who keeps learning stays young. And that's by Henry Ford. And hopefully everyone,
2:12.6	we have all these incredibly young listeners. I know we've been using the terminology of elderly
2:17.6	and elderly elderly. I'm just trying to figure out if you continue to learn what does that do to
2:23.3	your risk of a bad outcome from COVID. All right, so polio, as you just heard, don't check your
	...

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