TWiV 934: Clinical update with Dr. Daniel Griffin

This Week in Virology

Vincent Racaniello

Vincent, Microbe, Medicine, Microbiology, Racaniello, Infection, Virus, Virology, Pathogen, Infectious, Twiv, Science & Medicine

4.8 • 2.2K Ratings

🗓️ 10 September 2022

⏱️ 52 minutes

🔗️ Recording | iTunes | RSS

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Summary

In his weekly clinical update Dr. Griffin discusses variant influenza virus infections: recommendations for identification, treatment, and prevention for summer and fall 2022, low levels of monkeypox virus neutralizing antibodies after MVA-BN vaccination in healthy individuals, using the right tools at the right time for SARS-COV-2 infection, onset and window of SARS-COV-2 infectiousness and temporal correlation with symptom onset, transmission of SARS-COV-2: a review of viral, host, and environmental factors, antibody persistence and safety through 6 months after heterologous orally aerosolized Ad5-nCoV in individuals primed with two-dose vaccine, timely administration of tocilizumab improves outcome of hospitalized COVID-19 patients, administration of anti–SARS-COV-2 monoclonal antibodies after US Food and Drug Administration deauthorization, and clinical and genetic risk factors for acute incident venous thromboembolism in ambulatory patients with COVID-19. Subscribe (free): Apple Podcasts, Google Podcasts, RSS, email Become a patron of TWiV! Links for this episode 2022 recommendations for Influenza infections (CDC) Low levels of monkeypox neutralizing antibodies after vaccination (medRxiv) Using the right tools during SARS-CoV-2 infection (ESMED) Onset and window of SARS-CoV-2 infectiousness with symptom onset (The LANCET) Transmission of SARS-COV-2 (ACP Journals) PAXLOVID patient eligibility screening checklist (FDA) Remdesivir fact sheet for providers (Veklury) Bebtelovimab fact sheet for providers (FDA) Administration of anti–SARS-COV-2 monoclonal antibodies (JAMA) Clinical and genetic risk factors for thromboembolism (JAMA) Administration of tocilizumab improves outcomes (PLOS One) Antibody persistence and safety through 6 months (medRxiv) Improve risk score for thromboembolism (mdCalc) Contribute to Floating Doctors fundraiser at PWB Dr. Griffin’s treatment guide (pdf) Letters read on TWiV 934 Timestamps by Jolene. Thanks! Intro music is by Ronald Jenkees Send your questions for Dr. Griffin to [email protected]

Transcript

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0:00.0	This week in virology, the podcast about viruses, the kind that make you sick.
0:10.3	From micro TV, this is twiv this week in virology, Episode 934 recorded on September 8th,
0:21.0	2020-22. I'm Vincent Rackenello and you're listening to the podcast all about viruses.
0:27.7	Joining me today from New York, Daniel Griffin.
0:32.8	Hello everyone and joining us from the UK, Vincent.
0:37.2	I am here in Manchester, UK where sadly the queen has just died, yes.
0:42.8	Yeah, I heard that today and that is that is a loss.
0:46.6	Yeah, what a wonderful individual who really lived through so much of history.
0:52.2	Yes, indeed, but everyone is out on the streets in restaurants and having a good time.
0:58.3	It doesn't seem to be causing a dampener on the spirits of the brits.
1:03.7	Oh, interesting. Yeah, I was, well, I had heard there was supposed to be 10 days of morning,
1:08.8	so we'll see what form that takes. As long as they keep the planes running out of England,
1:15.4	that's fine with me. Well, I will start with my quotation. If one does not know to which port one is
1:22.0	sailing, no wind is favorable. And that's by Seneca, the Roman philosopher.
1:28.0	I think right now I was on the Brian Lair show earlier today and a lot of people are confused.
1:33.5	They're not really sure. What's the next step here in New York? They just
1:37.7	removed the masking mandates on all public transportation. The new bivalent boosters have rolled out.
1:45.8	A lot of people are left with a lot of questions like where are we headed? What does this mean?
1:50.0	And so we're going to continue with our commitment to give you the science to help you navigate,
1:56.5	to help you get some sense of which port you are sailing towards that you don't feel just lost.
2:02.7	But I'm going to start off with influenza, right? I'm pushing. I'm pushing those influenza
2:08.0	vaccines. Get your flu shots. Get your flu jabs. I'm not sure if our listeners get the CDC
	...

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