TWiV 903: COVID-19 clinical update #116 with Dr. Daniel Griffin

This Week in Virology

Vincent Racaniello

Vincent, Microbe, Medicine, Microbiology, Racaniello, Infection, Virus, Virology, Pathogen, Infectious, Twiv, Science & Medicine

4.8 • 2.2K Ratings

🗓️ 28 May 2022

⏱️ 48 minutes

🔗️ Recording | iTunes | RSS

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Summary

In COVID-19 clinical update #115, Dr. Griffin discusses croup association with infection surge, rhinovirus co-circulation in children, shedding following vaccination, high vaccine efficacy in children 6 mo-5 yr, vaccine protection for hospitalized patients, convalescent plasma as post-exposure prophylaxis, real-world effectiveness of PAXLOVID, effectiveness of PAXLOVID in reducing hospitalization, infection rebound after PAXLOVID, relapse of symptomatic infection after PAXLOVID, remdesivir and bebtelovimab fact sheets for providers, guidelines on usage of anticoagulation drugs, long covid symptoms after vaccination, excess mortality in MA, infection sequelae and immunity, and post infection conditions among adults. Subscribe (free): Apple Podcasts, Google Podcasts, RSS, email Become a patron of TWiV! Links for this episode Croup association with infection surge (PIDS) Rhinovirus co-circulation in children (Science Direct) Infection shedding following vaccination (MedRxiV) High vaccine efficacy in children 6 months to 5 years (Pfizer) Protection of vaccine against hospitalized patients (IDSA) Convalescent plasma as post-exposure prophylaxis (IDSA) Real-world effectiveness of PAXLOVID in Hong-Kong (MedRxiV) Effectiveness of PAXLOVID in reducing hospitalization (The Lancet) Infection rebound after PAXLOVID (CDC) Relapse of symptomatic infection after PAXLOVID (Research Square) Remdesivir fact sheet for providers (Veklury) Bebtelovimab fact sheet for providers (FDA) Guidelines on usage of anticoagulation drugs (ASH) Long covid symptoms after vaccination (BMJ) Excess morality in Massachusetts (JAMA) Infection sequelae and immunity (Annals of Internal Medicine) Post infection conditions among adults (CDC) Contribute to FIMRC fundraiser at PWB Dr. Griffin’s treatment guide (pdf) Letters read on TWiV 903 Timestamps by Jolene. Thanks! Intro music is by Ronald Jenkees Send your questions for Dr. Griffin to [email protected]

Transcript

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0:00.0	This week in virology, the podcast about viruses, the kind that make you sick.
0:10.4	From microbe TV, this is Twiv this week in virology, episode 903 recorded on May 26th, 2022.
0:20.8	I'm Vincent Dracanello and you're listening to the podcast all about viruses joining me today
0:26.6	from New York. Daniel Griffin. Hello, everyone. So I understand you don't want to do another hour
0:32.9	update, Daniel. Well, actually, maybe that's what my quotation this week is about. Maybe that was
0:39.0	a little too much. So the quotation will get right into it. The best doctor gives the least
0:45.9	medicine. And that's by Ben Franklin. So I'm going to start right ahead, Vincent, by mentioning
0:50.9	your pick from twiv902, the article physicians spreading misinformation on social media,
0:58.5	do right and wrong answers still existed medicine. It was published in New England Journal of
1:02.6	Medicine. I'm also going to lament that this is behind a paywall. Because I really think,
1:08.5	it's stuff like this, you know, needs to be out there for everyone, not just what,
1:13.9	academicians who, you know, are like basically just nodding their heads saying, yes, yes, we,
1:18.7	we need this to be part of the discussion. But I will say the first sentence I thought was
1:22.9	golden medicine has a truth problem in the era of social media and heavily politicized science.
1:31.8	Truth is increasingly crowdsourced. If enough people like share or choose to believe something,
1:38.8	others will accept it as true. Beautiful. That's absolutely the problem we have, right, Daniel?
1:44.1	Yeah. It's so true. I will say that I'm thinking a lot of physicians and scientists should clarify
1:51.7	when they say something. And they should say, this is evidence based. This is what the science
1:58.4	shows. Instead of just giving an opinion and then hoping that when they're right, they can then
2:05.8	retweet that back out there and say, see, I knew, I knew, you know, because yeah, you'll be,
2:12.1	you'll be right, you know, just like a broken clock at least two times a day. But that's not
2:18.8	what science is about. Science is saying, I don't know. And then finding out the answer. If you go
	...

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