TWiV 887: Bonfire of the monocytes

This Week in Virology

Vincent Racaniello

Racaniello, Virus, Virology, Infection, Microbe, Infectious, Medicine, Microbiology, Science & Medicine, Vincent, Twiv, Pathogen

4.8 • 2.2K Ratings

🗓️ 10 April 2022

⏱️ 108 minutes

🔗️ Recording | iTunes | RSS

🧾️ Download transcript

Summary

TWiV explains why this season’s influenza vaccine is not protecting against mild to moderate disease caused by H3N2 virus, and that antibody-dependent entry of SARS-CoV-2 into monocytes is a major contributor to severe COVID-19. Hosts: Vincent Racaniello, Dickson Despommier, Rich Condit, and Amy Rosenfeld Subscribe (free): Apple Podcasts, Google Podcasts, RSS, email Become a patron of TWiV! Links for this episode Seasonal influenza vaccine effectiveness (MMWR) Properties of a dominant H3N2 variant (bioRxiv) Scott Henley on influenza vaccine growth in eggs (TWiV 480) Fc receptor dependent entry of SARS-CoV-2 into monocytes (Nature) Timestamps by Jolene. Thanks! Weekly Picks Dickson – Ketanji Brown Jackson confirmed to US Supreme Court Amy – Some threats just keep coming in waves Rich – Lady Bird Johnson Wildflower Center Vincent – Martijn Doolaard Listener Picks Ann – Immunological memory to SARS-CoV-2 infection and vaccines Chris – Isoplexis Intro music is by Ronald Jenkees Send your virology questions and comments to twiv@microbe.tv

Transcript

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0:00.0	This week in virology, the podcast about viruses, the kind that make you sick.
0:10.4	From microbe TV, this is twiv this week in virology episode 887 recorded on April 8th, 2022.
0:21.4	I'm Vincent Racken Yellow and you're listening to the podcast all about viruses.
0:25.6	Joining me today from Fort Lee, New Jersey, Dixon, day-pomye.
0:31.3	Well, they're Vincent and all the ships that see and everybody else.
0:34.8	Looking out my window and having it open for most of the day,
0:38.8	let in a most pleasant weather pattern. It's a Georgia O'Keefe afternoon.
0:44.7	The Puffy White clouds are all about even sized. It's about 68 degrees.
0:50.3	Light wind, beautiful, beautiful, beautiful day. Wish this podcast were being haveled outdoors, but it's not.
0:58.2	Today is nice and sunny as you know, as you've just said.
1:01.8	And we had two previous days of cloudiness and it just emphasizes how much better your psyche is when it's sunny.
1:08.8	Also joining us from Austin, Texas, rich, condit.
1:13.6	Hi, everybody. 76 degrees is sunny. Also, gorgeous. It's a beautiful, beautiful spring day here in Austin, Texas.
1:22.9	And from New York, Amy Rosenfeld.
1:25.7	Hello.
1:26.9	Hey, Amy.
1:27.7	It's a look like out the window there.
1:29.7	I got white Puffy clouds. I was going to say and it's my favorite time in the year because it's
1:36.3	the Masters. I think Tiger is screwing it up.
1:40.0	However, I do have some other news tomorrow is the birthday of Malika, who is a listener and is
1:45.3	currently in a PhD program. And it's very interested in working one day on vaccine development.
1:51.6	She believes strongly in global vaccine availability and equity. Her favorite group of viruses are
	...

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