TWiV 1128: Clinical update with Dr. Daniel Griffin

This Week in Virology

Vincent Racaniello

Vincent, Microbe, Medicine, Microbiology, Racaniello, Infection, Virus, Virology, Pathogen, Infectious, Twiv, Science & Medicine

4.8 • 2.2K Ratings

🗓️ 6 July 2024

⏱️ 38 minutes

🔗️ Recording | iTunes | RSS

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Summary

In his weekly clinical update, Dr. Griffin discusses the fourth US case of H5N1 human infection and reminds the audience of the definition of “pasteurization” before reviewing the recent statistics on SARS-CoV-2 infection, where to find PEMGARDA, the effectiveness of molnupiravir and dexamethasone, convalescent plasma, what to do when healthcare workers succumb to SARS-CoV-2 infection, how an EEG can be used to look for signatures of cognitive decline after SARS-CoV-2 infection and what we observed 2 years following SARS-CoV-2 infection for tissue-resident T cell and viral RNA persistence. Subscribe (free): Apple Podcasts, Google Podcasts, RSS, email Become a patron of TWiV! Links for this episode Fourth case human infection associated with an ongoing multistate outbreak of A(H5N1) (CDC) Human H5N1 in Colorado and thedefinition of pasteurization (CIDRAP) Is “raw” milk more risky than pasteurized (Annenberg Public Policy Center) COVID-19 national trend (CDC) COVID-19 deaths (CDC) Winter, spring, summer and fall COVID-19 surges? (CDC) Where to get pemgarda (Pemgarda) Unable to access Pemgarda, gotta call Daniel (microbeTV) CDC Quarantine guidelines (CDC) Early phase of SARs-CoV-2 infection (COVID.gov) NIH COVID-19 treatment guidelines (NIH) Infectious Disease Society guidelines for treatment and management (ID Society) Drug interaction checker (University of Liverpool) Molnupiravir safety and efficacy (JMV) Molunpiravir works: reduces hospitalizations and deaths due to COVID-19 and all-cause mortality (CID) Convalescent plasma recommendation for immunocompromised (ID Society) What do when your heathcare provider is infected with SARS-CoV-2 (CDC) Managing healthcare staffing shortages (CDC) Steroids,dexamethasone at the right time (OFID) Benefits of dexamethasone, reversal of monocyte dysfunction for severe COVID-19 (Cell) Anticoagulation guidelines (hematology.org) EEG signatures for cognitive decline after SARS-CoV-2 infection (BMC Medicine) Tissue resident T-cells and viral RNA 2 years after SARS-CoV-2 infection (Science Translational Medicine) Contribute to our Floating Doctors fundraiser Letters read on TWiV 1128 Dr. Griffin’s COVID treatment summary (pdf) Timestamps by Jolene. Thanks! Intro music is by Ronald Jenkees Send your questions for Dr. Griffin to [email protected]

Transcript

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0:00.0	This week in virology, the podcast about viruses, the kind that make you sick.
0:07.0	From Microbe TV, this is Twive, this weekend virology, episode 1128, recorded on July 4th, 2024.
0:22.0	I'm Vincent Rachin-yellow and you're listening to the podcast, all about viruses.
0:27.0	Joining me today from New York, Daniel Griffin.
0:31.0	Hello everyone.
0:33.0	And I guess you don't have a 4th of July tie on, do you Daniel?
0:37.0	No, I probably should have found one that had a lot of like blue and red and white and all that that kind of stuff I actually am not sure what this
0:45.6	potai is my son Barnaby tried to use there's a Google program where you like look at
0:51.2	stuff and it tells you it could it doesn't know what it is either
0:53.7	it's some sort of microbe and and people can who are on I guess YouTube can see
0:59.4	this and yeah let me know well I don't even know if I didn't remember what this was. I knew at some point.
1:05.5	So all right, let's jump right into it. It's July 4th. I'm not going to keep people too long. No promises, of course, but let us start with our quotation.
1:16.4	And this is from Sir David Attenborough.
1:19.8	People must feel that the natural world is important and valuable and beautiful and
1:26.4	an amazement and a pleasure. And you know it made me think of just science
1:31.9	right I mean what is science about
1:33.8	science is about understanding and exploration and staying curious and
1:38.3	and just appreciating just how complex and beautiful and intricate this world we live in is.
1:45.5	And you know, when I hear a lot of this sort of anti-science, like basically,
1:49.1	don't look there, don't touch that, don't do that.
1:52.4	It's just an antithetical to this whole just you know nature and
1:56.8	everything around us is amazing and wonderful and fascinating and we're we are
	...

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