TWiV 1103: Jason 'Spike' McLellan

This Week in Virology

Vincent Racaniello

Vincent, Microbe, Medicine, Microbiology, Racaniello, Infection, Virus, Virology, Pathogen, Infectious, Twiv, Science & Medicine

4.8 • 2.2K Ratings

🗓️ 7 April 2024

⏱️ 65 minutes

🔗️ Recording | iTunes | RSS

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Summary

Vincent travels to the University of Texas in Austin to speak with speak with Jason McLellan about his career and his research on the SARS-CoV-2 spike protein, including the effect of adding two proline residues, its effect on other viral spike glycoproteins, and general approaches to vaccine design. Hosts: Vincent Racaniello and Rich Condit Guest: Jason McLellan Subscribe (free): Apple Podcasts, Google Podcasts, RSS, email Become a patron of TWiV! Links for this episode MicrobeTV Discord Server MicrobeTV store at Cafepress Become a member of ASV (asv.org) The New City by Dickson Despommier Prefusion-stabilized SARS-CoV-2 spikes (Science) Structure-based vaccine design (Curr Opin Immunol) Prefusion-stabilized SARS-CoV-2 S2-only antigen (Nat Comm) Stabilized coronavirus spike stem elicits broadly protective antibody (Cell Rep) Timestamps by Jolene. Thanks! Intro music is by Ronald Jenkees Send your virology questions and comments to [email protected]

Transcript

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0:00.0	This Week in Virology, the Podcast About Viruses, the kind that make you sick.
0:07.0	From Microbe TV, this is Twive this weekend, Virology. A special episode recorded on March 11,
0:19.4	2024. I'm Vincent Dracken-yellow and you're listening to the podcast all about viruses.
0:27.0	Today we are coming to you from Austin, Texas.
0:31.0	We're at the University of Texas and right here next to me from
0:35.8	Austin, Rich Condit. Hi everybody, I'm just looking up the weather. It's, by the
0:42.3	way, do you do the weather on Tuevo? I did the weather. It's, by the way, do you do the weather on Twevo? I did the weather yesterday on
0:45.6	Twevo. Was that unusual? Sometimes. It's really just the thing on Tweave.
0:50.9	Okay. It's 64 most part. It's
0:53.0	64 degrees outside. It's absolutely gorgeous. This is the best time of the year.
0:58.0	The blue bonnets are up. Man, driving up on Mopac. This just lousy with blue bonnets and whatever those
1:04.9	mopac are and stuff
1:06.4	but it's a road
1:07.9	that's what we did yesterday
1:09.2	uh... was a different road mopac is special they got
1:12.3	wildflowers more on Mopac is special. They got wildflowers more on Mopac.
1:14.7	We went to Johnson City yesterday.
1:16.5	Yeah.
1:17.5	And anyway, went to the science mill and recorded the Tweva 100 there.
1:22.1	It was really, have you been to the science mill?
1:24.6	It's very cool.
1:26.0	I mean, I was impressed actually.
	...

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