TWiV 1102: Clinical update with Dr. Daniel Griffin

This Week in Virology

Vincent Racaniello

Vincent, Microbe, Medicine, Microbiology, Racaniello, Infection, Virus, Virology, Pathogen, Infectious, Twiv, Science & Medicine

4.8 • 2.2K Ratings

🗓️ 6 April 2024

⏱️ 49 minutes

🔗️ Recording | iTunes | RSS

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Summary

In his weekly clinical update, Dr. Griffin reviews recent statistics on the circulation of measles and influenza before addressing Vincent’s comment on measles inclusion in the clinical respiratory PCR panel, the latest statistics on influenza and COVID-19 circulation, if inflammatory cytokines and anti-viral antibody function synergistically, if administration of peptide agonists of the glucagon-like or sodium-glucose pump can reduce disease severity, restates the guidelines for spring administration of COVID vaccines boosters, discusses the emergency use application of a pre-exposure prophylactic. revised guidelines for how to treat respiratory viral infection guidelines by the CDC, continues to dispel the myth of viral rebound, revised guidelines for SARS-CoV-2 treatment and how to treat respiratory viral infections, when to use steroids and the benefits of convalescent plasma, what do when healthcare workers succumb to SARS-CoV-2 infection, if remdesivir or paxlovid can reduce cardiovascular adverse events and the first finding of the two-year longitudinal study on long COVID. For more information about this body of work, listen to TWiV 1088. Subscribe (free): Apple Podcasts, Google Podcasts, RSS, email Become a patron of TWiV! Links for this episode Measles tracking (CDC) What happens when measles is included in commercial syndromic PCR panels (MMWR) Influenza/flu surveillance (CDC) Influenza on the Texas ranch (Statnews) Sequence analysis of highly pathogenic avian influenza from Texas (CDC) Influenza/flu map (CDC) COVID-19 hospital admissions (CDC) COVID-19 national trend (CDC) COVID-19 wastewater testing (biobot) Variant tracker (CDC) Variant hospital admissions (CDC) Can inflammatory cytokines and antibodies play nicely to prevent COVID-19 mortality (IJID) Association of GLP-1RA and SGLT-2i to modulate COVID-19 severity (Diabetes Therapy) Spring COVID-19 booster recommendations (CIDRAP) Older adult spring booster available (CDC) Advisory committee for immunization practices spring 2024 COVID-19 boosters (CDC) EUA for pemgarda (FDA) CDC Quarantine guidelines (CDC) NIH COVID-19 treatment guidelines (NIH) Molnupiravir safety and efficacy (JMV) Convalescent plasma recommendation for immunocompromised (IDSociety) CDC Quarantine guidelines (CDC) NIH COVID-19 treatment guidelines (NIH) What do when your heathcare provider is infected with SARS-CoV-2 (CDC) Managing healthcare staffing shortages (CDC) Steroids,dexamethasone at the right time (OFID) Anticoagulation guidelines (hematology.org) Remdesivir and cardiac adverse events in hospitalized patients (CID) Long COVID evidence based review TWiV shout out (TWiV 1088) Longitudinal study reveals long COVID symptom peaks and nadirs (OFID) Paxlovid lowers risk of cardiovascular disease in COVID-19 patients with autoimmune disease (BMC Medicine) Contribute to our ASTMH fundraiser at PWB Letters read on TWiV 1102 Dr. Griffin’s COVID treatment summary (pdf) Timestamps by Jolene. Thanks! Intro music is by Ronald Jenkees Send your questions for Dr. Griffin to [email protected]

Transcript

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0:00.0	This Week in Virology, the Podcast About Viruses, the kind that make you sick.
0:07.0	From Microbe TV, this is Twive this week in virology
0:15.2	episode 1102 now 1102 recorded on April 3rd, 2024.
0:25.0	I'm Vincent Rachin-yellow and you're listening to the podcast all about viruses.
0:30.3	Joining me today from New York, Daniel Griffin.
0:33.2	Hello everyone.
0:34.8	On this rainy, stormy night.
0:37.2	Is it rainy and stormy where you are?
0:39.0	You know, I usually don't talk about the weather, but the weather is fairly intrusive as of late.
0:46.0	Intrusive. I would argue that humans are intrusive. Yes, no thunder, thunder collapse, the
0:52.1	rain will never, seems never to be willing to stop and you know I live in an old house menson that was built in the 1800s
0:58.9	So whatever it rains the water comes in so I wear my shoes to come down to this recording studio as I walk
1:05.9	through the water. Well that's terrible. Well speaking of wearing what's on your bow tie today?
1:10.8	Ooh what could I possibly have? So I don't know if you could zoom in, but this is a
1:15.8	blue bow tie and it has these little red ribbons. So this is the HIV Awareness Bow Tie.
1:25.0	Right, wonderful.
1:26.4	And I have a few of them.
1:27.2	I have one that's, it's gold with the red on there.
1:30.5	It's got a few different ones.
1:36.7	All right, well, let jump right in. I'm glad that you you weathered the storm, literally, Benson and made it here. And I actually, this is perfect. You know we're talking about nature and the weather because I am going to start off with a Rachel Carson quotation.
1:50.0	I think we're challenged as mankind has never been challenged before to prove our maturity and our mastery, not of nature, but of ourselves.
2:01.0	And that's from 1962. It's not like today which would be even more appropriate, right?
	...

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