TWiV 1045: Less Lassa, CRISPR RNA viruses

This Week in Virology

Vincent Racaniello

Vincent, Microbe, Medicine, Microbiology, Racaniello, Infection, Virus, Virology, Pathogen, Infectious, Twiv, Science & Medicine

4.8 • 2.2K Ratings

🗓️ 17 September 2023

⏱️ 109 minutes

🔗️ Recording | iTunes | RSS

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Summary

TWiV reviews a Lassa virus mRNA vaccine that confers protection against disease without inducing neutralizing antibodies, and a CRISPR-based method for engineering the genome of RNA viruses. Hosts: Vincent Racaniello, Alan Dove, Rich Condit, Brianne Barker, and Angela Mingarelli Subscribe (free): Apple Podcasts, Google Podcasts, RSS, email Become a patron of TWiV! Links for this episode MicrobeTV Discord Server MicrobeTV store at Cafepress Research assistant position in Rosenfeld Lab CBER/FDA (pdf) Virologist Bob Lamb dies (Northwestern Now) Lassa virus mRNA vaccine (Nat Commun) CRISPR engineering of RNA viruses (Sci Adv) Letters read on TWiV 1045 Timestamps by Jolene. Thanks! Weekly Picks Angela – More than 5,000 new species discovered in Pacific deep-sea mining hotspot (journal article) Brianne – The story of our universe may be starting to unravel Rich – Sunlight Changes Unequally All Year Long Alan – Arm swing asymmetry in overground walking Vincent – The Farm at the Javits Center Listener Pick Asal – Ig Nobel Prizes honor zombie spiders, rock-licking scientists, and a clever commode Intro music is by Ronald Jenkees Send your virology questions and comments to [email protected]

Transcript

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0:00.0	This week in virology, the podcast about viruses, the kind that make you sick.
0:10.4	From microbe TV, this is TWIV, this week in virology, episode 1045, recorded on September 15,
0:19.6	20, 23. I'm Vincent Racken Yellow and you're listening to the podcast all about viruses.
0:27.1	Joining me today from Austin, Texas. Rich Condit.
0:30.8	Hi, everybody. I'm just booting up the weather here. Yes. Austin, Texas, get this 84 degrees.
0:39.8	Man, that's like 20 degrees less than when I last spoke to you. And there's been rain
0:48.1	the past couple of days. And so we're all really happy about that. It's kind of, I guess it's
0:54.4	clearing up now. So it's sunny ish. But I think we're out of the worst of it.
0:59.6	That's gotten much cooler here. I can't find the temple. I'll let Brienne do it.
1:03.2	Also joining us from Madison, New Jersey, Brienne Barker. Hi, it's great to be here. And here
1:08.4	it is 72 Fahrenheit and beautifully sunny. We've had a lovely last couple of days.
1:14.9	From Western Massachusetts, Alan Dove. Good to be here. It is 67 Fahrenheit, 19C,
1:21.6	overcast. And we have somewhere far out off the cape, somewhere to our east is
1:30.7	remnants of tropical storm, Lee, which is supposed to bring storm surge to the cape and islands.
1:37.0	And we're getting no rain out of it, which is a nice relief because we have been deluged with rain
1:43.2	for the past couple of weeks. Yeah. And from Montreal, Canada, Angela Mingur,
1:49.5	hey, everyone. So for the first time, maybe the first time, it's not the coldest in Montreal.
1:55.2	So it's 70 Fahrenheit and 21C. So it's a bit colder where Alan's at. And it's partially cloudy,
2:02.5	kind of sunny ish. I'm not complaining. We've also had a lot of rain. And it's been getting
2:06.9	pretty cold at night. You can definitely feel the fall in the air. Yeah, all of a sudden it got
2:12.7	chilly. Well, it is September 15 after all. We had a heat wave last week, though. It was really
2:20.1	hot here. I'm not sure if if everyone else also experienced this or maybe was it 10 days ago now,
	...

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