TWiV 1044: Clinical update with Dr. Daniel Griffin

This Week in Virology

Vincent Racaniello

Vincent, Microbe, Medicine, Microbiology, Racaniello, Infection, Virus, Virology, Pathogen, Infectious, Twiv, Science & Medicine

4.8 • 2.2K Ratings

🗓️ 16 September 2023

⏱️ 43 minutes

🔗️ Recording | iTunes | RSS

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Summary

In his weekly clinical update, Dr. Griffin discusses the immunogenicity and reactogenicity of coadministration of COVID-19 and Influenza vaccines, interim effectiveness estimates of 2023 southern hemisphere influenza vaccines in preventing Influenza-associated hospitalizations, genome-wide association study of susceptibility to RSV hospitalization in young children Subscribe (free): Apple Podcasts, Google Podcasts, RSS, email Become a patron of TWiV! Links for this episode Immunogenicity and reactogenicity of coadministration of COVID-19 and Influenza vaccines (JAMA) Effectiveness estimates of Influenza vaccines in preventing associated hospitalizations (CDC) Genome-wide association study of susceptibility to RSV hospitalization in children (JID) Performance of rapid antigen tests to detect SARS-CoV-2 infection (AIN) Safety and immunogenicity of XBB.1.5-containing mRNA vaccines (medRxiv) C.D.C. director explains why you should get the latest Covid booster (Nytimes) Optimal duration of systemic corticosteroids in COVID-19 treatment (OFID) Timing and predictors of loss of infectivity among healthcare workers with COVID-19 (CID) Effect of famotidine on cognitive and behavioral dysfunctions induced in post-COVID-19 infection (JPR) Contribute to our Floating Doctors fundraiser at PWB Letters read on TWiV 1044 Dr. Griffin’s COVID treatment summary (pdf) Timestamps by Jolene. Thanks! Intro music is by Ronald Jenkees Send your questions for Dr. Griffin to [email protected]

Transcript

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0:00.0	This week in virology, the podcast about viruses, the kind that make you sick.
0:10.5	From micro TV, this is TWIV, this week in virology, episode 1044, recorded on September 14,
0:20.4	2020-23. I'm Vincent Racken-Ello, and you're listening to the podcast all about viruses.
0:27.6	Joining me today from New York, Daniel Griffin. Hello, everyone. So Daniel, should everybody
0:34.7	over six months of age get the new booster? Well, we will certainly be discussing that.
0:39.7	All right, I can't wait. I'm sure you're waiting for my sage advice, Vincent. But let's start
0:48.1	with my quotation. Let us remember, one book, one pen, one child, and one teacher can change the
0:55.7	world, and that's by Malala. And for a lot of folks, it's tied back to school. And so I thought
1:03.3	that was appropriate for this time of year. And also, what else is on everyone's mind? Influenza,
1:09.6	I'm sure. And I actually really like this. I don't know if our listeners have heard about the
1:15.3	wild-to-mild campaign for flu vaccines. And I'm going to leave a link in, but Brenda Goodman
1:22.4	wrote a really nice piece about this in CNN Health. And I'm pleased to see the messaging is much
1:28.4	better here. So just let me read the beginning of this piece, because I think this really,
1:34.4	we've missed the point on, I think, a lot of communication. So some Americans have given up
1:39.5	on flu shots because almost everyone remembers the season when they got one and then got sick anyway.
1:46.2	Right. So now the U.S. CDC wants to reset expectations about what these annual vaccines can
1:55.2	and can't do. So it's rolling out new ads. It hopes we'll increase confidence in the vaccines with
2:01.0	a clear straightforward message. The flu vaccine won't keep a person from getting sick, but it will
2:08.3	tame the infection, taking it from wild to mild. And they've actually, they've quoted Bill Schaffner.
2:17.3	He's an ID doc down at Vanderbilt. With these respiratory viruses, flu included, the vaccines
2:23.2	aren't very good at preventing mild disease. They're much better at preventing the serious
2:27.8	complications. And I think we have not been very clear in presenting that information.
	...

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