TWiV 1046: Clinical update with Dr. Daniel Griffin

This Week in Virology

Vincent Racaniello

Vincent, Microbe, Medicine, Microbiology, Racaniello, Infection, Virus, Virology, Pathogen, Infectious, Twiv, Science & Medicine

4.8 • 2.2K Ratings

🗓️ 23 September 2023

⏱️ 47 minutes

🔗️ Recording | iTunes | RSS

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Summary

In his weekly clinical update, Dr. Griffin discusses wastewater surveillance data as a complement to emergency department visit data for tracking the incidence of influenza A and RSV, chatbot-delivered online intervention to promote seasonal Influenza vaccination during the COVID-19 pandemic, temporal assessment of disparities in California COVID-19 mortality by industry, modeling the impact of a high-uptake bivalent booster scenario on the COVID-19 burden and healthcare costs in New York City, can high COVID-19 vaccination rates in adults help protect unvaccinated children, Nirmatrelvir/Ritonavir use and hospitalizations or death in previously uninfected non-hospitalized high-risk population with COVID-19, Optimal duration of systemic corticosteroids in COVID-19 treatment, and vaccination after developing long COVID. Subscribe (free): Apple Podcasts, Google Podcasts, RSS, email Become a patron of TWiV! Links for this episode Wastewater surveillance data as a complement to tracking incidence of influenza A and RSV (CDC) Chatbot-delivered online intervention to promote seasonal influenza vaccination (JAMA) Temporal assessment of disparities in California COVID-19 mortality by industry (AOE) CDC/HICPAC’s plan to weaken guidance for health care respiratory protection and infection control (NNU) Modelling the impact of a high-uptake bivalent booster scenario on COVID-19 burden (The Lancet) Can high COVID-19 vaccination rates in adults help protect unvaccinated children? (ES) Paxlovid use and hospitalizations or death in previously uninfected high-risk population with COVID-19 (JID) Optimal duration of systemic corticosteroids in COVID-19 treatment (OFID) Vaccination after developing long COVID (IJID) Contribute to our Floating Doctors fundraiser at PWB Letters read on TWiV 1046 Dr. Griffin’s COVID treatment summary (pdf) Timestamps by Jolene. Thanks! Intro music is by Ronald Jenkees Send your questions for Dr. Griffin to [email protected]

Transcript

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0:00.0	This week in virology, the podcast about viruses, the kind that make you sick.
0:10.4	From micro TV, this is TWIV, this week in virology, episode 1046, recorded on September 21,
0:20.9	2023. I'm Vincent Draken yellow and you're listening to the podcast all about viruses,
0:28.2	joining me today from New York, Daniel Griffin. Hello, everyone. Daniel, I went to my
0:35.1	doc today and we got to talking about COVID and he said, yeah, rebound is a thing, but it's really rare.
0:41.6	I can't escape it. Oh my gosh. Okay, kill me now. All right, we'll talk about that, but
0:52.6	let's start off with a quotation. I actually was listening to one of the other TWIVs and
0:58.8	Vincent, you mentioned the book Fever, the hunt for a new killer virus. Also one of my favorites.
1:03.7	Oh, look at that. This is the 1970 copy that I have had for years. Yeah, that's great.
1:09.6	I was given a copy by one of the characters in the book. Yeah, so you gave me a picture of
1:17.2	the autograph inside it. Yeah. Yeah. Yeah. So here we go. In these times, the predictability of
1:23.6	viruses creates a situation which is as delicate as a hand grenade with the pin pole, the only
1:28.8	answer is constant vigilance. People seem to have forgotten that. I think the current updated
1:35.9	version is the the only answer is to put our head in the sand. Exactly right.
1:45.1	Well, let's take our head out of the sand for a moment. We'll start with flu RSV. Actually,
1:49.5	really, this is a waste water. So flu and RSV all in one with the MMWR waste water surveillance
1:57.2	data as a complement to emergency department visit data for tracking incidents of influenza A,
2:03.4	that's the epidemic and respiratory sensational virus was constant August 2022 through March 2023.
2:12.0	And really what we're seeing here is it's all in the figures. And so people should take a little time.
2:17.8	But basically, there's a there's a positive correlation between the two surveillance systems.
2:23.7	The waste water surveillance basically shows that numbers start to go up and we actually get a
2:29.6	little bit of a warning. So a wastewater goes up for flu and then we start to see ED visits for flu.
	...

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