TWiV 1012: Clinical update with Dr. Daniel Griffin

This Week in Virology

Vincent Racaniello

Vincent, Microbe, Medicine, Microbiology, Racaniello, Infection, Virus, Virology, Pathogen, Infectious, Twiv, Science & Medicine

4.8 • 2.2K Ratings

🗓️ 3 June 2023

⏱️ 38 minutes

🔗️ Recording | iTunes | RSS

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Summary

In his weekly clinical update, Dr. Griffin discusses the potential for recurrent Mpox outbreaks among gay, bisexual, and other men who have sex with men, association between SARS-CoV-2 variants and frequency of acute symptoms, prospective study of key correlates for household transmission of SARS-CoV-2, Pfizer’s PAXLOVID™ receiving FDA approval for adult patients at high risk of progression to severe COVID-19, efficacy and safety of antimicrobial stewardship prospective audit and feedback in patients hospitalized with COVID-19, development of a definition of postacute sequelae of SARS-CoV-2 infection, COVID-19 and risk for mental disorders among adults in Denmark, risk of new post-COVID mental disorders higher only in older patients. Subscribe (free): Apple Podcasts, Google Podcasts, RSS, email Become a patron of TWiV! Links for this episode Potential for recurrent Mpox outbreaks among men who have sex with men (CDC) Association between SARS-CoV-2 variants and frequency of acute symptoms (OFID) Key correlates for household transmission of SARS-CoV-2 (OFID) PAXLOVID receiving FDA approval for patients at high risk of severe COVID-19 (Pfizer) Efficacy and safety of antimicrobial stewardship prospective audit and feedback in patients with COVID-19 (The Lancet) Development of a definition of postacute sequelae of SARS-CoV-2 (JAMA) COVID-19 and risk for mental disorders among adults in Denmark (JAMA) Risk of new post-COVID mental disorders higher only in older patients (CIDRAP) Contribute to our FIMRC fundraiser at PWB Letters read on TWiV 1012 Dr. Griffin’s COVID treatment summary (pdf) Timestamps by Jolene. Thanks! Intro music is by Ronald Jenkees Send your questions for Dr. Griffin to [email protected]

Transcript

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0:00.0	This week in virology, the podcast about viruses, the kind that make you sick.
0:10.4	From microbe TV, this is TWIV, this week in virology, episode 2012, recorded on June 1st, 2023.
0:22.4	I'm Vincent Drakenyllo, and you're listening to the podcast all about viruses.
0:27.7	Joining me today from New York, Daniel Griffin. Hello, everyone. Daniel, in the old days,
0:35.7	I used to ask you, how are the COVID numbers? But not really a reliable question any longer,
0:41.8	since there's not a lot of testing. It's really gotten to be tough. As we've talked about a lot
0:47.0	of the deaths are now silent. People are dying in facilities. Decisions are being made just to
0:52.9	make them comfortable. It's tough. It'll be interesting to see what happens this summer,
0:58.9	and be interesting to see what happens next fall going into the winter. I will. I certainly will.
1:07.3	Oh, in my bow tie, this is my plague, or cineapestus bow tie. Nice. Very good. We'll be talking about
1:14.0	the modern plague. Let me start with my quotation, and this is by Marcus Aurelius from his
1:20.4	meditations, never let the future disturb you. You will meet it if you have to the same weapons of
1:26.9	reason, which today arm you against the present. And we're going to be talking a bit about long COVID.
1:32.7	So I just thought this would be a nice quotation, sort of an encouraging quotation for clinicians
1:38.3	on those still suffering. But I actually have a bunch of, I think, really interesting, important
1:44.1	news this week. I'm actually going to think this is Vincent telling you ahead of time. It's going to
1:47.9	be one of our best episodes ever, if you can believe that. All right. So all right. Just,
1:53.5	we'll start with a couple. So right off the bat, RSV, we just learned Wednesday, May 31,
1:59.1	2023, that their advisors had recommended the US FDA approved a brisvo. This is Pfizer's vaccine
2:07.6	for the prevention of respiratory, sensational virus in older adults, as we've discussed before.
2:13.5	This is the bivalent RSV pre-fusion F vaccine for the prevention of lower
2:19.3	respiratory tract disease caused by RSV in individuals 60 years and older. This is an unadjuvanted
	...

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