Transposition of the Great Arteries (2nd edition)

The Zero to Finals Medical Revision Podcast

Thomas Watchman

Life Sciences, Education, Medical Finals, Medicine, Surgery, Health & Fitness, Paediatrics, Medical Student, Medical Education, Medical Exams, Medical School, Medical Revision, Science, Learn Medicine, Finals Revision, Obstetrics And Gynaecology

4.8 • 678 Ratings

🗓️ 31 January 2025

⏱️ 6 minutes

🔗️ Recording | iTunes | RSS

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Summary

This episode covers transposition of the great arteries. Written notes can be found at https://zerotofinals.com/paediatrics/cardiology/transpositionofthegreatarteries/ Questions can be found at https://members.zerotofinals.com/ Books can be found at https://zerotofinals.com/books/ The audio in the episode was expertly edited by Harry Watchman.

Transcript

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0:00.0	Hi, this is Tom and in this episode I'm going to be going through Transposition of the Great Arteries.
0:10.5	And you can find notes at zero to finals.com and in the zero to finals pediatrics book.
0:16.6	And you can find flashcards and questions to train your knowledge at members.0.0.com.
0:23.8	So let's jump straight in.
0:26.1	Transposition of the great arteries involves swapped attachments of the aorta and the pulmonary trunk.
0:34.0	The right ventricle pumps blood into the aorta and the left ventricle pumps blood into the pulmonary vessels.
0:42.3	Blood from the systemic venous system drains to the right side of the heart and is pumped straight back into the aorta and the systemic arterial system.
0:53.3	Blood from the pulmonary veins drains into the left side and the systemic arterial system.
0:58.8	Blood from the pulmonary veins drains into the left side of the heart and is pumped straight back into the pulmonary arteries.
1:03.7	These two separate circulations do not mix.
1:08.5	During pregnancy, fetal development is typically normal as gas and nutrient exchange
1:15.6	happens in the placenta and blood does not need to travel to both the lungs and the systemic
1:21.9	circulation. However, transposition of the great arteries becomes immediately life-threatening after birth.
1:31.6	The newborn will be cyanotic, as the blood in the systemic circulation has not been to the lungs
1:38.0	and picked up oxygen, so is therefore de-oxygenated blood.
1:44.4	Immediate survival depends on a shunt which connects the systemic and the pulmonary circulation.
1:51.3	This can occur across a patent ductus arteriosus, an atrial septal defect, or a ventricular septal defect.
2:02.6	Let's go through the presentation.
2:05.5	The defect is often diagnosed during pregnancy with the antinatal ultrasound scans.
2:13.0	Close monitoring is necessary during the pregnancy and arrangements are made for specialist management
2:19.5	immediately after birth. When the defect is not detected antinatally, it will present with
2:27.3	severe cyanosis shortly after birth. A patent ductus arteriosis or a ventricular septal defect can initially compensate by allowing blood to mix between the systemic circulation and the lungs.
	...

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