Welcome to the Dr. Gundry podcast, where Dr. Stephen Gundry shares his groundbreaking research from over 25 years of treating patients with diet and lifestyle changes alone.

Dr. Gundry and other wellness experts offer inspiring stories, the latest scientific advancements, and practical tips to empower you to take control of your health and live a long, happy life.

You know, there's a really interesting compound that occurs in nature, that occurs in several foods,

and maybe one of the kind of hidden secrets to longevity that you need to know about. And I'm talking about

spermidine. You may recall a term called autophagy. Atopagy actually means self-eat. In aging, there are

essentially two ways a old cell is destroyed. One is called apoptosis. It

literally explodes and spews everything all over the place. That's actually a bad way. On the other hand,

the opposite is called autophagy.

And atophagy basically means, okay, everything in here is worn and old. Let's recycle these

components, buff them up and reuse them again. And it turns out the more you can induce autophagy and the less you

induce apoptosis, the longer you live and the longer you live well. What does that have to do

with spermodyte? Spermidine promotes autophagy, not apoptosis.

So I want to talk about spermodyne.

Stay with me for a few minutes because we're going to get a little nerdy and it's going to be kind of sciencey.

But I promise you it'll be worth it because you really want to know about spermene.

Okay, spermanine is a naturally occurring compound. We actually make it. It's part of a class of

compounds called polyamines. In mice, oral administration of polyamines has been shown to repair

their intestinal mucosa and reduce inflammation.

In fact, if you've read gut check, polyamines increase intestinal alkaline phosphatase.

That's a really good thing to have.

Here's the fun part.

Spermene was discovered in human semen. Yes, that's where it got its name.

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