4.7 • 789 Ratings
🗓️ 22 February 2023
⏱️ 57 minutes
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0:00.0 | Welcome back to plenary session. Today I stopped by the office. I stopped by the office at |
0:06.5 | UCSF and I had a discussion with Dr. Tom Newman. He is Professor Emeritus here at UCSF. He was a |
0:13.3 | practicing pediatrician. He is an evidence-based medicine expert. He's in clinical epidemiologist. |
0:20.1 | He's a superb teacher. We have a discussion |
0:22.5 | about public health, about a little bit about clinical epidemiology. In the discussion, he talks |
0:30.0 | about a YouTube video of mine that he had watched. He had a bone to pick with me. Something about |
0:35.1 | it he didn't like, 100%. And it was a good discussion, I think. |
0:40.5 | Before I play the discussion, since you audio listeners may not have seen the video, I think I'll |
0:46.2 | give you the audio for the video. So you'll know what we're talking about. This was a provocative |
0:51.0 | video, I think, but also a truthful video, I think, but you'll hear what we say about it. |
0:55.9 | It's about public health lying about natural immunity. So today's episode, I'm going to play the audio track of this thing. It's only going to be like 17 minutes. |
1:03.7 | Then you're going to hear our discussion about it. And hopefully soon you hear Tom Newman again. And we're going to do some stuff together that we've been planning, and I think it'll be a lot of fun. |
1:12.0 | So on that positive note, this is what you get on plenary session. |
1:16.3 | You get pretty much whatever I want you to get, because if you don't like it, you can switch the episode. |
1:20.1 | I'm going to be back with more oncology stuff. |
1:23.2 | I got to talk about Rukaparib. |
1:25.0 | I got to talk about Karma 3aparib. I got to talk about Karma 3. Not to say there. |
1:29.7 | Rukaparib, lousy control arm, inappropriate use of crossover. OS differences null. |
1:36.0 | Of course, they're going to fault that on crossover, but the equally plausible explanation is it doesn't do that much anyway. |
1:42.5 | The PFS benefit is scant it's really a terrible |
1:45.8 | study karma three the control arm severely underperforms they do so so badly that you really have to |
1:51.9 | wonder what the hell was going on in that study they underperform even their own power calculation |
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