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The Playbook With David Meltzer

Thinking Decades Ahead in Healthcare

The Playbook With David Meltzer

David Meltzer, Entrepreneur.com

Entrepreneurship, Business, Careers

4.61.9K Ratings

🗓️ 20 May 2025

⏱️ 21 minutes

🧾️ Download transcript

Summary

In today’s episode, I sit down with Jim Tananbaum, founder and CEO of Foresite Capital, to talk about how a background in medicine and math can shape the future of healthcare. He explains how early research exposure at Harvard and MIT led to a strategy that connects long-term vision with measurable impact. We get into why sequencing all 20,000 genes is more useful than collecting endless data, and how AI is helping tailor healthcare without overcomplicating it. Jim also shares how purpose, persistence, and the right partnerships have guided his decisions across decades of transformation in biotech, venture capital, and personal health.

Transcript

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0:00.0

Welcome to Entrepreneurs the Playbook. I'm David Meltzer. Super excited to have a special guest here.

0:06.0

An extraordinary venture capitalist. He is the founder of Foresight Capital. Jim Tannenbaum.

0:10.9

Welcome to the playbook. Great to be here, Dave. Thanks for having me.

0:14.1

You know, our backgrounds are not similar. You got accepted to Harvard. I got rejected twice.

0:22.8

You're a doctor. I'm about to get an honorary doctorate this week, actually. Yes, I will not be calling myself doctor. I do have a

0:28.6

jurist doctorate, which may or may not be comparatively equal. But it's interesting because I

0:35.7

see later on in my career, people attaching themselves to careers,

0:41.1

industries and jobs. You, you went to med school at Harvard. Yeah. And then later on,

0:47.8

applied business aptitude to what you learned as your core skill set competency, let's call it.

0:56.1

I went to law school and then applied business to what I had learned in law school.

1:02.2

The reason I got hired at Lee Steinberg, for those of you that may not know the most

1:07.8

notable sports agent in the world, they made the movie Jerry McGuire.

1:10.9

I got hired in 48 hours after meeting Lee Steinberg, not because I was a great lawyer.

1:16.1

I was an oil and gas lawyer, a maritime lawyer who ended up working for West publishing

1:20.6

in the internet and then going to Silicon Valley and raising hundreds of millions of dollars.

1:25.6

But Lee hired me, not because I was a great sports

1:28.6

agent, not because I had this, you know, amazing law background, but I was the only one who at the

1:37.2

highest level had a technology background and a venture capital background. And he saw in the early

1:42.3

2000s the future of sports was going to be

1:45.0

in venture and technology. That was his vision. I think he was right. And I'm certainly glad

1:50.6

that he trusted me to run the sports agency with that type of background. You have done the

1:56.8

exact same thing. You're a doctor, like a real doctor, not like an honorary degree doctor

...

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