The Supplement That Reversed Aging in Human Trials, with Dr. Anurag Singh

The Dr. Hyman Show

Dr. Mark Hyman

Health & Fitness, Nutrition, Medicine

4.6 • 8.7K Ratings

🗓️ 25 June 2025

⏱️ 82 minutes

🔗️ Recording | iTunes | RSS

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Summary

On this episode of The Dr. Hyman Show, I sit down with Dr. Singh—Chief Medical Officer at Timeline and a pioneer in mitochondrial science—to talk about what’s really driving fatigue, muscle loss, and accelerated aging. Together, we break down the simple, science-backed ways to support your cells so you can feel stronger. You’ll learn: • Why your mitochondria impact energy, metabolism, and how you age • The role Urolithin A supports cellular renewal—and what that means for your strength • How you can pair fasting, movement, and nutrients for better energy and recovery • Why personalized strategies can support your energy, focus, and strength over time This episode is packed with takeaways for boosting your cellular energy—and it’s one of the most practical conversations I’ve had on the science of longevity. View Show Notes From This EpisodeGet Free Weekly Health Tips from Dr. Hymanhttps://drhyman.com/pages/picks?utm_campaign=shownotes&utm_medium=banner&utm_source=podcastSign Up for Dr. Hyman’s Weekly Longevity Journalhttps://drhyman.com/pages/longevity?utm_campaign=shownotes&utm_medium=banner&utm_source=podcastJoin the 10-Day Detox to Reset Your Healthhttps://drhyman.com/pages/10-day-detoxJoin the Hyman Hive for Expert Support and Real Resultshttps://drhyman.com/pages/hyman-hive This episode is brought to you by Seed, Pique, BON CHARGE, Paleovalley and Timeline. Visit seed.com/hyman and use code 25HYMAN for 25% off your first month of Seed's DS-01® Daily Synbiotic. Head to piquelife.com/hyman to get 20% off + a free beaker and frother today. Go to boncharge.com and use code DRMARK to save 15% on your PEMF mat today. Get nutrient-dense, whole foods. Head to paleovalley.com/hyman for 15% off your first purchase. Support essential mitochondrial health and save 20% on Mitopure. Visit timeline.com/drhyman to get 20% off today.

Transcript

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0:00.0	You're saying that you could take this compound made by bacteria as a supplement.
0:04.0	You're going to see about a 10% improvement in strength and cardiovascular fitness and a reduction in inflammation.
0:09.0	Mostly the trials we have run in placebo control randomized trials, we see in the absence of exercise,
0:15.0	in the absence of changing their diets, you get about a 10, 12% improvement in strength,
0:20.0	you get about a 10% improvement in
0:21.9	B.O2 levels. Leading immunologist, Dr. Anarag Singh. Explores how mitochondria and inflammation shape
0:29.0	our health. Aging and energy. Exercise is the best mitochondrial drug. So just getting people moving
0:34.7	in their 70s and 80s, three times a week for 30 minutes.
0:37.9	That's the basic, you know, having a rejuvenation effect on the mitochondria.
0:41.3	You've got three ways to sort of soup up your mitochondria and make more than one is exercise.
0:45.7	Two is...
0:50.3	In functional medicine, we always start with the gut.
0:53.3	It's at the core of nearly every aspect of health, from digestion and immune function
0:57.6	to brain and skin health.
0:58.8	Your gut microbiome regulates inflammation, absorbs nutrients, and maintains the integrity
1:03.1	of your gut barrier.
1:04.1	That's why I take and recommend seeds DS01 daily symbiotic, a next-level probiotic designed
1:08.9	to go beyond digestion.
1:10.1	With 24 clinically
1:11.3	studied probiotic strains and a pomegranate-based prebiotic, seeds DS-01 supports gut immune function,
1:17.5	gut barrier, integrity, and even heart health through the gut liver axis. But here's what's really
1:22.4	exciting. Research now shows that gut health directly impacts skin health through the gut skin axis.
	...

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