The Science of Looking Younger, Longer | Episode 6

Lifespan with Dr. David Sinclair

Lifespan Communications LLC

Health & Fitness

4.9 • 4.9K Ratings

🗓️ 9 February 2022

⏱️ 70 minutes

🔗️ Recording | iTunes | RSS

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Summary

In Episode 6 of the Lifespan podcast, Dr. David Sinclair and co-host Matthew LaPlante discuss cosmetic aging and how to improve skin, nails, and hair. They talk about why superficial aging occurs and how external signs of aging are often a reflection of biological age. The latest science behind various beautifying therapies is highlighted, including newer interventions like low-level laser therapy and platelet-rich plasma injections. Thank you to our sponsors: Athletic Greens - https://athleticgreens.com/sinclair Levels - https://levels.link/sinclair InsideTracker - https://insidetracker.com/sinclair Our Patreon page: https://www.patreon.com/davidsinclair Lifespan book: https://amzn.to/3sUqurT Dr. David Sinclair Social: Instagram Twitter Facebook Matthew LaPlante's Social: Twitter To stay up to date with David's work to democratize biological age testing and insights, visit tallyhealth.com. Timestamps: (00:00:00) Launching Episode Six: Combating Cosmetic Aging & Improving Skin, Nails & Hair (00:02:54) Estrogen, Progesterone, and Menopause (00:09:51) Thanking the Sponsors (00:12:57) The Pinch Test, Epidermal Thinning, and Foot Ulcers (00:18:29) Skin and Biological Aging (00:23:19) Cellular Senescence, Ultraviolet Light, and Skin Aging (00:28:15) Collagen, Keratin, and Skin Health (00:33:38) A Quick Aside about Nails (00:34:45) Autophagy and Retinoids (00:36:57) Resveratrol, NAD Boosters, and Hyaluronic Acid (00:41:44) Botox, Skin Peels, and Microneedling (00:43:28) No Duh Stuff: Sun Damage, Smoking, Alcohol, and Bad Food (00:45:42) Hair Loss and Hair Graying (00:49:45) Topical Treatments, Pills, and Dihydrotestosterone (00:55:19) Frickin Laser Beams: Low-level Laser Therapy (00:57:59) Platelet-rich Plasma (PRP) Injections (01:00:11) Hair Aging, Stress, and Gray Hair Reversal (01:06:11) Targeting Aging Upstream (01:07:37) Today’s Takeaways (01:09:25) Subscription and Support Options For the full show notes, including the peer-reviewed studies, visit the Lifespan podcast website. Please note that Lifespan with Dr. David Sinclair is distinct from Dr. Sinclair's teaching and research roles at Harvard Medical School. The information provided in this show is not medical advice, nor should it be taken or applied as a replacement for medical advice. The Lifespan with Dr. David Sinclair podcast, its employees, guests and affiliates assume no liability for the application of the information discussed. Special thanks to our research assistants, Adiv Johnson & Sarah Ryan.

Transcript

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0:00.0	Welcome to the Lifespan Podcast, where we discuss the science of aging and how to be healthier at any stage of life.
0:09.5	I'm David Sinclair. I'm a professor of genetics at Harvard Medical School and co-director of the Polyff Glenn Center for Biology of Aging Research.
0:18.0	This series of podcasts is about why we age and things we can do to slow, stop and even reverse that process.
0:25.5	Last episode, we talked about really cutting-edge science and procedures that people are currently doing with their doctors and what they might be doing in the coming years.
0:35.5	Today, we're going to talk about what you can do to slow, stop and even reverse the aging of your outside, the outside of your body.
0:43.5	I'm joined today by my lovely co-author and co-presenter, co-human co-ed, no.
0:52.5	Co-conspirator.
0:54.5	Matthew Lapland, welcome.
0:56.5	Hey, let's do this again. I was not, you know this. I was not so excited about this episode.
1:01.5	When you told me, when Wonder Boy Rob told us that it was going to be about cosmetic aging, I pooped this.
1:09.5	Then we prepped for it. We've been having great conversations over the last few days.
1:13.5	I'm actually really excited about this conversation.
1:16.5	That's true, especially the parts about improving your sexual function. I thought you were excited about the most.
1:21.5	That's not in this episode. We'll have an episode on that.
1:25.5	No, today we're talking about cosmetic aging and we're talking about the difference between interventions that are only aimed at appearance and interventions that might impact both appearance and aging.
1:37.5	We had to cover a number of topics including how to keep your hair, skin and nails looking young and even reversing aspects of that process.
1:46.5	We should say here there's nothing wrong with things that are purely aesthetic, that only work to make ourselves look good.
1:55.5	Because those things might not impact our biological aging, but they can affect us socially, emotionally, mentally, they can make our lives better.
2:04.5	We're not going to poop who, I've used the word poop who now is several times.
2:08.5	We're not going to denigrate interventions that are only aimed at appearances, but we are going to talk more about and center of focus around interventions that might also have an anti-aging effect.
2:21.5	Exactly. There are cover-ups. We're going to talk a little bit about Botox and other creams.
2:26.5	But really, I think what's most exciting and most powerful are the technologies that are available now and shortly that can boost the body's ability to fight aging.
	...

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