The Natural ‘Ibuprofen’ That Doesn’t Wreck Your Gut
The Evan Brand Show
Evan Brand, BCHN, FNTP
4.8 • 810 Ratings
🗓️ 26 February 2026
⏱️ 30 minutes
🧾️ Download transcript
Summary
Ibuprofen works but frequent use can be rough on the gut. In this episode, we break down why certain natural compounds may support pain relief through overlapping inflammation pathways without the same gastrointestinal downside seen with NSAIDs.
Check out more functional medicine strategies at evanbrand.com/fame where you can get access to functional medicine courses and masterclasses. Join me for a LIVE webinar on gut health - register at https://www.evanbrand.com/gut and check out Better Belly Premium at evanbrand.com/belly-premium if you'd like Evan's guidance and a discount on the OAT and GI Map!
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Transcript
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| 0:00.0 | Hello, welcome to the podcast. We're going to dive in here in just a minute. Just wanted to announce the launch of the app. It's going to be called Fame Mobile, Functional Academy of Medicine and Epigenetics. This is going to be on the Apple Play Store. We're working on the Google Play Store as well. So if you're in my group or if you want to be in my group, we're going to have an even more convenient way to get |
| 0:21.5 | you functional medicine care at your fingertips. That way you don't have to go and log in a |
| 0:25.3 | bunch of places. You'll click on the app. You'll be able to navigate straight to our group calls, |
| 0:29.6 | which I do every two weeks live. It is probably the highlight of my week, every week. I hope you |
| 0:36.8 | join. Evanbrand.com has all the details |
| 0:39.5 | on both the one-on-one practice as well as the group program where you'll get the organic |
| 0:44.2 | acids and the GI to get you started. We're going to have a fun time today. We're chatting about |
| 0:48.8 | all things inflammation, what's wrong with Aleve and ibuprofen and cortisone shots and these conventional approaches that really just don't work compared to the functional stuff? |
| 0:58.6 | Sure, you can take a bunch of opiates and get addicted and hooked and have all kind of crazy issues, but I don't want you to do that. |
| 1:04.3 | I want you to do natural things and I want you to look into your gut. |
| 1:07.1 | Today we're going to be also talking about the surprising link between your gut and your |
| 1:11.4 | arthritis and inflammation and pain. If you have gut infections, it can definitely drive arthritis. |
| 1:17.8 | Stay tuned. We're going to break all this down. Dr. Jay and I are going to dive deep into the |
| 1:21.9 | studies today and break down some of these key nutrients that you should have in your pantry to get |
| 1:26.2 | yourself better. So without further ado, let's get into the show.ora roots.com. Get the microbiome reset bundle, the detox bundle, the honey. There's so much good stuff there, even if you can't budget for the labs. Look there and you're going to be in a better place than you are right now, I promise. And we are live. Is that the J. |
| 1:44.4 | In The House with Evan Brand. |
| 1:45.6 | Today we're going to be talking all about inflammation, natural compounds to reduce |
| 1:50.6 | inflammation. |
| 1:51.0 | We'll be talking about some of the biochemical pathways, what's happening under the hood, |
| 1:55.9 | getting to the root cause, and looking at some of the side effects or maybe conventional |
| 1:59.1 | medications and comparing it to some of the natural options that we have at our fingertips. |
| 2:04.0 | Evan, how we do, man? |
... |
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