The Menopause Gut: How Your Microbiome Controls Your Hormones, Mood, and Metabolism with Cynthia Thurlow
The Resetter Podcast with Dr. Mindy
Dr. Mindy Pelz
4.7 • 1.4K Ratings
🗓️ 22 April 2026
⏱️ 75 minutes
🧾️ Download transcript
Summary
We've had a lot of important menopause conversations, but nobody's given us the manual for the gut until now.
Cynthia Thurlow is a nurse practitioner, host of the Everyday Wellness podcast, and author of the brand new book, The Menopause Gut. And in this conversation, she and Dr. Mindy pull back the curtain on one of the most overlooked and misunderstood pieces of the entire menopause puzzle: the estrobolome.
This conversation is a must-listen for any woman in perimenopause or beyond who feels like she's doing everything right and still not feeling better. It's also essential if you've ever taken the pill, struggled with gut issues, or wondered whether your mood, sleep, and waistline might have more to do with your microbiome than your hormone panel.
For more resources related to today's episode, visit the podcast episode page: https://www.drmindypelz.com/ep336
Connect with Cynthia Thurlow:
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The Menopause Gut: https://www.penguinrandomhouse.com/books/777129/the-menopause-gut-by-cynthia-thurlow-np/
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Instagram: https://www.instagram.com/cynthia_thurlow_/?hl=en
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Facebook: https://www.facebook.com/CHTWellness
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Twitter/X: https://x.com/_CynthiaThurlow
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Podcast: https://podcasts.apple.com/us/podcast/everyday-wellness-midlife-hormones-menopause-and/id1435214303
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Substack: https://cynthiathurlownp.substack.com/
Connect with Dr. Mindy:
Disclaimer: This podcast is intended for educational and informational purposes only and is not a substitute for professional medical advice. Always consult a qualified healthcare professional before making changes to your diet, fasting routine, or lifestyle.
Transcript
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| 0:00.0 | On this episode of The Resetter podcast, I am bringing you back once again, Cynthia Thurlow. |
| 0:09.9 | Now, I got to tell you, Cynthia has been one of our most requested guests. |
| 0:15.2 | She and I have done two episodes on fasting. |
| 0:18.0 | She wrote a book called Intermittent Fasting Transformation for Women. |
| 0:22.6 | So we've united on the metabolic health of women over the years. And those of you have been |
| 0:28.2 | listening to the Resetter podcast for a while may have remembered those conversations. |
| 0:34.5 | Well, I am bringing her back today to talk about an extremely important piece of hormonal health that does not get enough attention. |
| 0:43.3 | And that is our gut microbiome. |
| 0:47.3 | Cynthia has a new book out called The Menopause Gut. |
| 0:51.3 | It is a much needed conversation in the menopause space right now. On this particular |
| 0:58.5 | episode, you're going to learn about a set of bacteria that we call the astrolome, which are |
| 1:04.6 | bacteria that break and detoxify estrogen. And it is this set of bacteria that is critical for your hormonal experience. |
| 1:15.3 | If this set of bacteria is off, your menopause journey may be incredibly turbulent. |
| 1:23.3 | So in this podcast episode, we talk about what do these specific bacteria do? |
| 1:29.4 | What parts of our health do they control? |
| 1:32.1 | What lifestyle habits that we have destroy them? |
| 1:35.9 | And most importantly, what do we do to bring these microbes back? |
| 1:40.7 | As you're going to learn in this podcast, these microbes not only break down estrogen, but they have a massive impact on insulin sensitivity as you go through menopause. |
| 1:52.4 | They have a massive impact on your moods as you go through menopause. |
| 1:57.5 | And there is a lot in this discussion about how these microbes affect sleep. |
| 2:04.0 | So if you're looking for a deeper conversation about how do you take your power back as |
| 2:11.2 | you're going through menopause, how do you have more control through this experience, |
... |
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