The Key to Managing Stress & Healing Your Mind | Dr. Nicole LePera
The Daily Motivation
Lewis Howes
4.8 • 960 Ratings
🗓️ 1 March 2026
⏱️ 7 minutes
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| 0:00.0 | Hi, my name is Lewis Howes and welcome to the Daily Motivation Show. |
| 0:12.5 | Do you think a depressive state comes from an obsessive thought process? |
| 0:18.6 | Like the more you think and ruminate on I'm'm not enough, I never have this, I suck, |
| 0:23.0 | I'm not worthy, I'm not deserving, the more I ruminate on it for longer, longer is that |
| 0:28.1 | what's going to put me in that state of being? |
| 0:30.5 | It's one of the factors. |
| 0:32.2 | It's not the only, the issue with depression and anxiety, and a lot of the things that |
| 0:36.6 | we're diagnosed with, myself |
| 0:38.3 | included, is that they're messengers of something deeper. So typically with depression, |
| 0:43.3 | there might and likely is something physiological also at play. There could be some gut issues |
| 0:49.3 | that are causing inflammation that is causing actual inflammation in the brain and causing those symptoms of depression. |
| 0:56.0 | There might be some nervous system activation, getting stuck in our parasympathetic, |
| 1:01.0 | in particular nervous system that results in that hypo energetic arousal when I have no energy, |
| 1:07.0 | I have no interest. |
| 1:09.0 | So typically it's thoughts and the physiology that then |
| 1:13.3 | maps on to thinking those thoughts for a very long time. Though my point of working holistically is to |
| 1:19.0 | acknowledge the whole story because I'm sure even a lot of listeners right now might have tried an |
| 1:24.5 | affirmation, tried to think of positive thought and not actually been |
| 1:28.2 | able to create change because likely they are again living in a state of physiological |
| 1:33.5 | dysregulation. |
| 1:34.5 | Right, right. |
| 1:35.5 | It's kind of like you have to have a holistic approach to what is the root, what's |
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