The Importance of Gut Health: Impacts Beyond Digestive Issues with Dr. Colleen Cutcliffe

The Root Cause Medicine Podcast

Kate Kresge

Alternative Health, Medicine, 810564, Health & Fitness

4.8 • 581 Ratings

🗓️ 15 June 2023

⏱️ 39 minutes

🔗️ Recording | iTunes | RSS

🧾️ Download transcript

Summary

Dr. Colleen Cutcliffe, Cofounder and CEO of Pendulum Therapeutics, is leading a dedicated team in their pursuit of groundbreaking and transformative solutions for gut health-related ailments, showcasing a remarkable passion for improving people's lives through revolutionary, safe, and effective microbiome interventions. In today's episode with Dr. Colleen Cutcliffe, you’ll hear us take a deep dive on: 1. The evolution of antibiotics and how their broad spectrum also harms the gut microbiome, potentially causing long-term issues like food sensitivities, chronic illnesses, and conditions beyond the digestive system, such as obesity and neurological disorders. 2. The recent discovery of the keystone probiotic strain Akkermansia, which resides in the gut lining, and its crucial role in preventing gut lining deterioration. 3. Akkermansia’s benefits, including producing proteins that stimulate GLP-1, a hormone involved in regulating insulin and glucose response to prevent high glucose spikes and promote weight loss. 4. How neurons in the gut communicate with the brain, influencing cravings and other functions, and recent studies indicate that neurological conditions like Parkinson's and Alzheimer's may manifest in gut neurons before brain cells. Order tests through Rupa Health, the BEST place to order functional medicine lab tests from 30+ labs - https://www.rupahealth.com/reference-guide Use code root20 for 20% off of your next purchase of Akkermansia - bit.ly/3p8qxkn

Transcript

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0:00.0	Today on the root cause medicine podcast. What your microbiome has co-evolved with you to do are a
0:06.7	wide variety of functions that are sort of pivotal to your health. If you think about it,
0:12.2	everything you eat is first metabolized by your stomach and then by your microbiome. And so if you
0:17.5	don't have these bugs, you're actually missing the things that help you metabolize your food fully effectively.
0:23.2	And so what ends up happening is that I should say it's not just antibiotics.
0:27.1	They're kind of the most potent way that you can disrupt your microbiome, but there's other ways your microbiome gets disrupted.
0:32.6	Hello, hello. I'm your host, Dr. Carrie Jones.
0:35.7	And today I'm talking with Dr. Colleen Cutcliffe,
0:38.9	the CEO and co-founder of the Uber Cool Microbiome Company called Pendulum. Dr. Cutcliffe is a
0:44.9	scientist with a PhD in biochemistry and microbiology from Johns Hopkins University. She's held
0:51.3	senior positions at multiple bioscience and pharmaceutical firms.
0:55.0	Her company Pendulum are the only makers of Acromancea, and honestly some other pretty cool
1:01.0	microbiome metabolic products as well. In fact, they were kind enough to gift me some bottles
1:06.0	after the fact, which I have been taking pretty faithfully the last month and definitely noticed a positive shift in my digestion.
1:13.4	I was absolutely thrilled to have her on for my own nerd curiosity, given what I know about acromancea, gut health, and even your glucose health.
1:23.8	In fact, I have a code for you. When you go to pendulum.com or hit that link in the show notes,
1:30.2	you can use root 20. That's R-O-O-O-T-2-0-2. You'll get 20% off your next purchase.
1:40.2	But before we get started, I want to talk to you about something that comes up pretty often on this podcast, and that, of course, are all sorts of supplements besides Pendulum.
1:49.9	In fact, there's a lot of confusion around supplements, and of course, you only want to take the best quality that uses top tier certified manufacturers and, most importantly, do third-party independent testing to make
2:03.0	sure what's on the label is in the capsule.
2:06.4	That's why I have teamed up with new ethics formulations as their chief medical officer.
2:11.0	The team already had a strong history in the supplement world, but started the company to
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