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Hey guys, before we get started, just a morning that there's a little swearing in this episode.

Okay, here's the show.

Recently, reporter Matthew Schneier met up with an up-and-coming actress, we'll call Allison.

It's not a real name, but it's what he called her in a story. Matthew writes for New York magazine.

She's an actress, she works film television, these sort of things, and she has always been or has generally been fairly slim.

But Allison was about to start promoting a new project, and she wanted to lose a little weight.

So, in December, she went on a course of some agglotide.

That's the generic name for diabetes drugs like ozempic, and while they are intended for type 2 diabetes, off-flabel use has exploded, including, of course, in Hollywood.

Matthew knew what Allison looked like, he'd seen her on screen. But when they met in person, he could tell something had changed.

The way I describe it in the piece is she looked to me like the kind of Instagram version of herself.

She wasn't skeletal, he wasn't concerned, but there was a difference.

Something looked a little bit kind of sharpened, and I wasn't surprised when I said, I knew that she was on this track, but I said, you know, what's different and said, you know, I'm down 10 pounds.

Matthew says they sat together drinking the coffees. He had a normal sized one and a piece of bread.

Allison had a tiny one, a no bread. She said she just wasn't interested in food.

Several people I spoke to, who have experienced with these medications, described feeling a real kind of disinterest, even bordering and disgust on food.

You know, they kind of had to force down their throats, essentially. One woman said to me, you know, I loved Brussels sprouts. Brussels sprouts were my favorite thing.

And I would be chewing them and thinking like, you know, when is this going to be over?

Today on the show, the era of a Zempic may just be beginning. What does it mean when a drug can profoundly alter weight, health, and a relationship with food?

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