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The Model Health Show

The Hidden Hormone Shift Driving Chronic Disease in Women - With Dr. Jessica Shepard

The Model Health Show

Shawn Stevenson

Fitness, Health & Fitness, Nutrition

4.87.3K Ratings

🗓️ 6 April 2026

⏱️ 49 minutes

🧾️ Download transcript

Summary

For decades, the transition of perimenopause and menopause has largely been ignored. But thanks to emerging data and passionate experts, the conversation is starting to shift and expand. Today, you’re going to learn about the hormones involved in menopause and their relationship to other health conditions.  Our guest, Dr. Jessica Shepherd is a board-certified OB/GYN, author, and leading voice in women’s health and longevity. Dr. Shepherd joins this episode of The Model Health Show for an important conversation on how women can thrive throughout perimenopause and menopause. She’s sharing science-backed insights from her book, Generation M.  In this interview, you’re going to learn about the health issues that women experience throughout perimenopause and menopause, and how to ease symptoms through lifestyle-based recommendations. Dr. Shepherd is a true expert on the latest data surrounding menopause, and I know you’re going to find value in her accessible approach. So click play and enjoy the show!  In this episode you’ll discover: What percentage of American adults have a chronic disease. (0:26) The three main reasons why women are more susceptible to certain health issues. (2:46) Why the perimenopausal phase is like a dimmer switch. (6:41) The importance of body awareness during perimenopause. (7:51) How hormones are linked to cardiovascular disease. (10:00) What women need to know about osteoporosis. (13:17) The critical role of strength training for women. (16:59) How the thyroid is affected by hormonal shifts in menopause. (18:02) The connection between the thyroid, hot flashes, and menopause. (19:40) How metabolic syndrome can be caused by perimenopause and menopause. (22:28)  The benefits of hormone replacement therapy. (27:51) Why sleep is critical during perimenopause and menopause. (30:52) Dr. Shepherd’s prescription for diet and exercise for women in mid-life. (39:07) Items mentioned in this episode include: Themodelhealthshow.com/ourplace - Use code MODEL to save up to 40% OFF sitewide on toxin-free, ceramic coated cookware! Paleovalley.com/model - Use code MODEL for 15% off!  Generation M by Dr. Jessica Shepherd - Read more about living well through menopause! Modern Meno - Join Dr. Shepherd’s longevity and menopause community!  Connect with Dr. Jessica Shepherd Website / Instagram / TikTok Be sure you are subscribed to this podcast to automatically receive your episodes:  Apple Podcasts Spotify Soundcloud Pandora YouTube  This episode of The Model Health Show is brought to you by Our Place and Paleovalley.  For a limited time only, save up to 40% OFF during Our Place’s spring sale. Use my code MODEL at themodelhealthshow.com/ourplace.  Use my code MODEL at Paleovalley.com/model to save 15% sitewide on nutrient dense snacks, superfood supplements, and more.

Transcript

Click on a timestamp to play from that location

0:00.0

You are now listening to The Model Health Show with Sean Stevenson.

0:04.8

For more, visit themodelhealthshow.com.

0:10.1

Welcome to the model health show.

0:11.8

This is fitness and nutrition expert Sean Stevenson,

0:14.1

and I'm so grateful for you tuning in with me today.

0:17.7

On this episode, you're going to discover one of the hidden reasons for our skyrocketing

0:23.6

rates of chronic diseases in the United States. According to the CDC's latest data,

0:29.1

75% of American adults now have at least one chronic disease. Now, we know that this is a multifaceted issue, but there is a specific

0:40.4

hormonal change that's contributing to specifically five chronic conditions that are again

0:48.4

heavily influenced by the hormonal changes that happen in perimenopause and menopause. And today you're going to learn

0:56.8

some practical ways to defend against them. And you're also going to learn the truth about some

1:03.9

controversial treatments like hormone replacement therapy, aka H.R.T, and much more with our special guests.

1:13.3

And she is one of the world's foremost experts in this subject matter.

1:17.7

And without further ado, let's dive into this conversation with our special guest

1:20.5

and our topic of the day.

1:21.5

Dr. Jessica Shepard is a board-certified OBGYN, chief medical officer of hers, and author of Generation M, the chart-topping

1:31.0

book redefining women's health. A leading voice in women's wellness and longevity, she's a regular

1:35.8

all over major media, including Good Morning America, the Today Show, live with Kelly and Mark,

1:41.9

Vogue, Cosmopolitan, and many other media outlets.

1:45.2

With a no-nonsense approach and deep medical expertise, she's helping women cut through the noise,

1:51.7

take control of their health, and feel their best at every stage of life.

1:56.2

Let's dive in this conversation with the one and only Dr. Jessica Shepard.

...

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