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Commune with Jeff Krasno

The Gut-Brain Connection: How Stress, Trauma, and Shame Impact our Physiology with Dr. Will Cole

Commune with Jeff Krasno

Commune Media

Health & Fitness, Society & Culture

4.6654 Ratings

🗓️ 22 February 2025

⏱️ 84 minutes

🧾️ Download transcript

Summary

Leading functional medicine expert Dr. Will Cole discusses how chronic stress, unresolved trauma, and shame can dysregulate the neuroendocrine axis, leading to hormonal imbalances and inflammation. Discover the role of gut health, environmental toxins, and social media in shaping our well-being, and learn practical strategies to support healing, improve vagal tone, and cultivate resilience.


This episode originally aired on July 27, 2023.

Watch Dr. Will Cole’s Commune course, Intermittent Fasting, with a 14-day trial of Commune Membership. Sign up for free at onecommune.com/trial


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Transcript

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0:00.0

Welcome to the Commune Podcast. My name is Jeff Krasnow.

0:12.0

As we approach 700 episodes here on the Commune podcast, we are now republishing some of our most popular interviews with teachers and doctors who

0:22.6

now have full-length courses over on the commune course platform. This interview is from

0:28.9

23 with Dr. Will Cole. Will has been central to my health journey. So Will has been named

0:36.6

one of the top 50 functional medicine and

0:39.0

integrative doctors in the nation and runs one of the first functional medicine telehealth

0:44.2

centers in the world. He specializes in excavating the underlying root causes of chronic disease

0:50.3

and customizing a personalized precision medicine approach for conditions including thyroid

0:56.3

issues, autoimmune diseases, hormonal imbalances, and digestive and mental disorders. At the time of

1:03.4

this interview, Will had just published his book, Gut Feelings, Healing the Shame-Fueled

1:08.9

relationship between what you eat and how you feel. Will shares that

1:13.8

clinical studies show us that chronic stress, unresolved trauma, shame, and environmental toxicity

1:20.6

can impact the body's underlying biochemistry, creating chronic inflammatory problems, metabolic dysfunction, and brain health

1:29.7

issues. Now, the fight or flight response is a natural adaptive biological feature, but modernity

1:36.6

has created an evolutionary mismatch. And when we're exposed to chronic stress, the HPA axis,

1:44.1

that's the hypothalamic pituitary adrenal axis,

1:47.6

increases cortisol and adrenaline levels. And this affects blood sugar, blood pressure,

1:53.1

heart rate, and increases inflammation. This is why managing stress response is essential

1:59.1

to fostering balance and homeostasis in the body.

2:03.8

I talk about this all the time in my book, Good Stress.

2:07.2

But fear not, we'll also outline actionable protocols that you can lean on to improve gut

2:13.5

function, such as consuming probiotic fermented foods.

...

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