The Cure for Cancer is Prevention, And It's Here
Finding Genius Podcast
Richard Jacobs
4.4 • 1K Ratings
🗓️ 7 October 2023
⏱️ 24 minutes
🧾️ Download transcript
Summary
Cancer survival exceeds 90% when detected during Stage I.
Novel technologies are making early detection easier, especially for cancers that usually aren't diagnosed until after metastasis has occurred.
Tune in to discover:
- The important distinction between multi-cancer early detection and liquid biopsy
- The benefits provided by looking for molecular signs of cancer rather than anatomical, such as by mammogram or colonoscopy
- How stage I cancer is defined
Eric Fung, MD, PhD, is Vice President of Clinical Development at Grail, a company with a mission to detect cancer early, before it has spread to other parts of the body. Unfortunately, as it currently stands, only a fraction of cancers are detected at Stage I, especially when it comes to cancers for which there are no screening guidelines.
Over the past 50 years, the primary focus in cancer research has been on therapeutics.
But many FDA-approved therapeutics have very little impact on survival rates, because when it comes down to it, the best way to reduce cancer mortality is to detect cancers early, when they can still be cured.
Fung explains how a new multi-cancer early detection (MCED) test called the Galleri test can detect the presence of 50 Stage I cancers, and with only a single blood draw. He also discusses the studies supporting the validity of this test, namely the Circulating Cell-free Genome Atlas (CCGA) study and prospective clinical study called PATHFINDER.
The Galleri test is now available to patients by prescription.
Press play to hear the full conversation and learn more at grail.
Episode also available on Apple Podcasts: apple.co/30PvU9C
Transcript
Click on a timestamp to play from that location
| 0:00.0 | Forget frequently asked questions. |
| 0:02.3 | Common sense. |
| 0:03.1 | Common knowledge. |
| 0:04.1 | Or Google. |
| 0:04.7 | How about advice from a real genius? |
| 0:06.9 | 95% of people in any profession are good enough to be qualified in license. |
| 0:11.3 | 5% go above and beyond. |
| 0:13.1 | They become very good at what they do. |
| 0:14.8 | But only 0.1% are real geniuses. |
| 0:18.2 | Richard Jacobs has made it his life's mission to find them for you. |
| 0:22.2 | He hunts down and interviews geniuses in every field. |
| 0:25.1 | Sleep science, cancer, stem cells, ketogenic diets, and more. |
| 0:28.6 | Here come the geniuses. |
| 0:30.3 | This is the Finding Genius podcast. |
| 0:32.8 | The Richard Jacobs. |
| 0:37.5 | Hello, this is Richard Jacobs with the Finding Genius podcast, now part of the Finding Genius |
| 0:42.1 | Foundation. |
| 0:43.2 | I have Dr. Eric Fung. |
| 0:44.4 | He's the vice president of clinical development at Grail Bio. |
| 0:47.7 | He's a bit about his bio. |
| 0:48.6 | He's an executive with experience in IVD test development, including biomarker and |
| 0:53.7 | discovery and validation, clinical trials, FDA submission, product launch. So it sounds like his experience goes through the whole life cycle of, you know, ideation to actual approval. And we're going to talk about his work at Grail. So Eric, thanks for coming. Thank you for having me. Yeah. You would tell me a bit about your background. How did you end up at Grail? |
... |
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