How Does Cancer Spread (Metastasize) to Other Parts of the Body and How to Prevent it?
Finding Genius Podcast
Richard Jacobs
4.4 • 1K Ratings
🗓️ 8 October 2023
⏱️ 28 minutes
🧾️ Download transcript
Summary
How can cancer metastasis be better understood through the study of the microbiome? By understanding how the microenvironment reaches its most beneficial state, researchers can better understand and treat metastasis.
Press play to learn:
- How can cells metastasize into various parts of the body
- Which factors play a role in metastasis
- Why cancers have tropisms
Sendurai A. Mani, a Professor, Department of Translational Molecular Pathology, shares his work to better understand metastasis in cancerous tumors.
Since one of the most dangerous aspects of cancer is its ability to travel throughout the body, it is in researchers' and patients' best interest to discover why.
This can be difficult, though, since cancer cells break the norm of normal cells.
It can be challenging to distinguish single cancer cells from normal cells since they excrete the same protein.
However, by explicitly studying the microenvironment, it may be easier to differentiate the cells for studies.
Want to learn more? Visit https://www.mdanderson.org/research/departments-labs-institutes/labs/mani-laboratory.html.
Episode also available on Apple Podcasts: apple.co/30PvU9C
Transcript
Click on a timestamp to play from that location
| 0:00.0 | Forget frequently asked questions, common sense, common knowledge, or Google, how about advice from a real genius? |
| 0:07.0 | 95% of people in any profession are good enough to be qualified in license, 5% |
| 0:12.0 | They become very good at what they do, but only 0.1% are real geniuses |
| 0:18.0 | Richard Jacobs has made his life's mission to find them for you. He hunts down and interviews geniuses in every field |
| 0:25.0 | in sleep science, cancer, stem cells, ketogenic diets, and more. Here come the geniuses. This is the Finding Genius Podcast |
| 0:33.0 | The Richard Jacobs |
| 0:38.0 | Hello, this is Richard Jacobs with the Finding Genius Podcast, now part of the Finding Genius Foundation |
| 0:43.0 | Well, today my guest is Sandoora Imani, he's a professor, Department of Translational Molecular Pathology |
| 0:49.0 | Part of the University of Texas, MD Anderson Cancer Center in Houston |
| 0:53.0 | I'm going to talk about cancer metastasis, so Imani, thanks for coming |
| 0:57.0 | Thank you, thank you Richard for hosting me and I special thanks to you for inviting scientists like me and then interviewing us |
| 1:06.0 | And then getting our perspective for your audience |
| 1:10.0 | Thank you |
| 1:11.0 | Oh, thank you very much, I appreciate it |
| 1:13.0 | So tell me about your research a little bit about your career path, how did you get to where you're at? |
| 1:18.0 | So I completed my PhD from a place called Indian Institute of Science, which is one of the premier institute in India |
| 1:26.0 | Then I came to MIT in Boston and I did my postdoctoral work with Professor Robert Weinberg |
| 1:33.0 | From there I moved to Houston to MD Anderson that I have been here for the last close to 14 years |
| 1:41.0 | And I'm a professor now a tenured professor at MD Anderson Cancer Center |
| 1:46.0 | So we're getting within cancer, are you focused on metastasis or what you're focused on? |
| 1:51.0 | So I am primarily interested in my lab, I would say we are interested in understanding the biology of cancer metastasis |
| 2:00.0 | So we use breast tissue or breast cancer as a primary kind of tumor model to study |
... |
Please login to see the full transcript.
Disclaimer: The podcast and artwork embedded on this page are from Richard Jacobs, and are the property of its owner and not affiliated with or endorsed by Tapesearch.
Generated transcripts are the property of Richard Jacobs and are distributed freely under the Fair Use doctrine. Transcripts generated by Tapesearch are not guaranteed to be accurate.
Copyright © Tapesearch 2026.