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Low Carb MD Podcast

The Cholesterol Code Movie | Dave Feldman and Jennifer Isenhart - E439

Low Carb MD Podcast

Drs. Brian Lenzkes & Tro Kalayjian

Medicine, Mental Health, Health & Fitness

4.81.2K Ratings

🗓️ 20 April 2026

⏱️ 99 minutes

🧾️ Download transcript

Summary

The Cholesterol Code is a gripping new documentary from Jennifer Isenhart that challenges one of medicine's most entrenched beliefs. Following Dave Feldman's unexpected health journey, the film dives into the controversy around cholesterol, uncovering new research and raising a powerful question: what if we've misunderstood it all along?

In this episode, Dr. Tro, Jennifer, and Dave talk about…

  • (00:00) Intro

  • (02:39) How the upcoming documentary film, The Cholesterol Code, came to be and how Jen crafted the film to be accessible to a wide audience

  • (08:06) How Jen turns scientific data into an engaging film

  • (15:33) The effort and passion Dave Feldman has poured into his research

  • (17:49) Why YOU should watch this film (Jen's answer)

  • (22:37) How Dave went from a curious software engineer to being one of the main forces driving research on cholesterol and metabolic disease

  • (26:24) Coining the term 'lean mass hyper-responder' and founding the Citizen Science Foundation

  • (31:19) Dave Feldman's critics and how to push back against dogmatic medical authoritarianism

  • (44:29) The good and the bad of cholesterol

  • (01:00:36) LDL, ApoB, and plaque progression

  • (01:06:36) Why YOU should watch The Cholesterol Code (Dave's answer)

  • (01:08:06) CAC, CCTA, ApoB, and LDL levels

  • (01:14:08) Medications that reduce arterial plaque

  • (01:16:19) Arterial plaque and the keto diet

  • (01:26:23) The biggest myths that were dispelled in The Cholesterol Code film

  • (01:29:27) Medical professionals who have come around to Dave and Jen's perspective on cholesterol

  • (01:33:32) Outro

For more information, please see the links below. Thank you for listening!

Links:

Please consider supporting us on Patreon: https://www.lowcarbmd.com/

Resources Mentioned in this Episode:

Jennifer Isenhart:

Dave Feldman:

Dr. Brian Lenzkes: 

Dr. Tro Kalayjian: 

Toward Health App

Join a growing community of individuals who are improving their metabolic health; together. 

Get started at your own pace with a self-guided curriculum developed by Dr. Tro and his care team, community chat, weekly meetings, courses, challenges, message boards and more. 

Apple: https://apps.apple.com/us/app/doctor-tro/id1588693888 

Google: https://play.google.com/store/apps/details?id=uk.co.disciplemedia.doctortro&hl=en_US&gl=US

Learn more: https://toward.health/community/

Transcript

Click on a timestamp to play from that location

0:00.0

Welcome to the Low Carb MD Podcast. No one is beyond help. No one is beyond hope.

0:07.2

Nothing said on the Low Carb MD podcast is medical advice. Please consult your own doctor before making any

0:13.7

lifestyle changes. Welcome everybody.

0:22.5

This is Dr. Trow Collasian.

0:24.5

This is the low-carb-md-d podcast if you're listening to our podcast.

0:28.9

And we're live on multiple social platforms right now.

0:32.5

So thank you for joining us.

0:34.3

And I have the pleasure of interviewing two people I would consider friends. If you've been

0:42.1

living under Iraq and don't know about a film that I'm about to tell you about, well,

0:49.1

now is your time to know about it, go out and learn about it, watch it, and learn about the two people that I'm

0:56.9

about to talk about who made this amazing documentary and film happen. I have Jen Eisenhardt,

1:06.2

who is a documentary filmmaker and one of the collaborators for the cholesterol code.

1:13.1

And she's also the producer and the director of Fat Fiction, which had, of course, was an

1:22.4

amazing documentary focus on metabolic health and nutrition.

1:28.9

We also have Dave Feldman, who I've had the pleasure of working on

1:34.2

on a couple of lipid papers.

1:38.5

He is an independent researcher, the founder of the cholesterol code,

1:43.3

and I'd say, and I'm not sure if this is true. And Dave,

1:46.8

you could maybe you could tell me if I'm right or wrong on this. You are the founder and the

1:53.1

coiner of the term lean mass hyper responders, which is a way of describing a lipid phenomenon we see in people who adopt metabolic approaches

2:06.4

like fasting and low carb.

2:09.4

Both of these people are friends of mine, super excited to have both of them here and just

...

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