Reanalyzing Nutritional Epidemiological Studies | Dr. Matt Calkins - #440

Low Carb MD Podcast

Drs. Brian Lenzkes & Tro Kalayjian

Medicine, Mental Health, Health & Fitness

4.8 • 1.2K Ratings

🗓️ 27 April 2026

⏱️ 80 minutes

🔗️ Recording | iTunes | RSS

🧾️ Download transcript

Summary

Dr. Matt Calkins is a physician focused on improving metabolic health through lifestyle-based care. Board-certified in family and obesity medicine, he is a strong advocate for low-carb and ketogenic nutrition as powerful tools to address obesity, diabetes, and chronic disease. He is passionate about helping patients reclaim their health through sustainable, evidence-based strategies.

In this episode, Drs. Tro, Brian, and Matt talk about…

(00:00) Intro
(06:40) Nutritional epidemiological studies and how they have informed public opinion on nutrition over the years
(13:15) How nutritional epidemiological studies should NOT be used
(21:20) Dr. Calkin's recent criticism of a nutritional epidemiological study making big claims from only observational data
(31:52) Why nutritional epidemiological studies are flawed and how they are misused by medical professionals, agencies, and laypeople alike
(42:07) Why doctors and medical professionals seem so averse to adapt and change as new scientific data comes out
(54:22) Why it is better to focus on the individual patient in front of you than to make assumptions about people in general based on nutritional epidemiological studies
(01:03:46) How Dr. Calkin's criticism was received by the authors of the study
(01:09:56) Why so many of bad epidemiological studies are published
(01:12:17) Outro

For more information, please see the links below. Thank you for listening!

Links:

Please consider supporting us on Patreon: https://www.lowcarbmd.com/

Dr. Matt Calkins:

Concordance between nutritional cohorts and randomized trials: biological confirmation or statistical consequence? A re-analysis of Stadelmaier et al.: https://sciprofiles.com/publication/view/aac50964f8442b33eb42921d37613629
X: https://x.com/MattCalkinsMD

Dr. Brian Lenzkes:

Website: https://arizonametabolichealth.com/
Twitter: https://twitter.com/BrianLenzkes?ref_src=twsrc^google|twcamp^serp|twgr^author

Dr. Tro Kalayjian:

Website: https://toward.health
Twitter: https://twitter.com/DoctorTro
IG: https://www.instagram.com/doctortro/

Toward Health App

Join a growing community of individuals who are improving their metabolic health; together.

Get started at your own pace with a self-guided curriculum developed by Dr. Tro and his care team, community chat, weekly meetings, courses, challenges, message boards and more.

Apple: https://apps.apple.com/us/app/doctor-tro/id1588693888

Google: https://play.google.com/store/apps/details?id=uk.co.disciplemedia.doctortro&hl=en_US&gl=US

Learn more: https://toward.health/community/

Transcript

Click on a timestamp to play from that location

0:00.0	Welcome to the Low Carb MD Podcast. No one is beyond help. No one is beyond hope.
0:07.2	Nothing said on the Low Carb MD podcast is medical advice. Please consult your own doctor before
0:13.1	making any lifestyle changes. Hello and welcome back to the low-carb MD podcast.
0:23.8	I'm outnumbered by some East Coast people here today.
0:26.8	Troll, how are you doing, man?
0:28.3	We're going to have a lot of fun today.
0:29.9	We're going to debunk some nutrition myths and, you know, propaganda.
0:34.9	So, you know, I'm always down for debunking propaganda. And we have
0:38.9	somebody who, you know, he's like a dark horse, you know, he's really like a dark horse.
0:45.8	I cannot tell you how immensely valuable and helpful he's been to the Society of Metabolic
0:51.9	Health practitioners, to my own practice.
0:56.4	And I have to, I'm very grateful for him and everything that he's done.
1:02.9	We have Dr. Matt Hawkins, who is a double board certified physician in family medicine
1:09.4	and obesity medicine.
1:11.3	He did his residency at Wake.
1:13.8	Actually, he started as an ER doc, and he's been on the podcast before,
1:17.3	but he started as the ER doc just to remind everybody.
1:20.7	And then he saw the light.
1:22.3	He said, I'm going to go to family medicine in primary care.
1:26.7	And he's essentially devoted the last, I'd say, probably
1:30.7	five years of his life to improving the entire field of metabolic health. He's published a number
1:40.8	of papers alongside with me and Dr. Lord Buchanan, Dr. Adrian Sotomoto,
	...

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