The Broccoli Molecule That Steers Estrogen Down the Right Pathway | Mara Labs

The Dr. Tyna Show

Dr. Tyna Moore

Alternative Health, Health & Fitness

4.9 • 1.7K Ratings

🗓️ 30 April 2026

⏱️ 85 minutes

🔗️ Recording | iTunes | RSS

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Summary

EP. 259: What if one compound from broccoli could influence detox pathways, estrogen metabolism, gut integrity, and even how your body handles modern environmental toxins like microplastics? In this episode, I sit down with David Roberts and Dr. John Gilday from Mara Labs to break down sulforaphane and why it plays such a unique role in metabolic and hormonal health. We talk about estrogen metabolism, NRF2 activation, inflammation signaling, gut barrier function, and emerging research around microplastics and cellular detox systems.→ For the next week, Dr Tyna Show loyal listeners can get an exclusive 25% off all Mara Labs products when you go to www.mara-labs.com/DRTYNA and use code DRTYNA at checkout. After May 7th, the code will return to the standard 15% off. Topics Discussed: → How does sulforaphane affect detox pathways → What does NRF2 do in the body → Can supplements help estrogen metabolism → How do microplastics affect hormones → What improves gut barrier function Sponsored By: → Mara Labs | For the next week, Dr Tyna Show loyal listeners can get an exclusive 25% off all Mara Labs products when you go to www.mara-labs.com/DRTYNA and use code DRTYNA at checkout. After May 7th, the code will return to the standard 15% off. On This Episode We Cover: → 00:00:00 - Introduction → 00:03:32 - Estrogen + Metabolism → 00:06:54 - AMPK + SIRT 1 → 00:12:42 - Supplement Comparisons → 00:17:47 - Cooked vs Raw Broccoli → 00:23:33 - Detox Phases → 00:27:13 - Microdosing GLP1 → 00:29:11 - Leaky Gut + Glyphosate → 00:31:51 - Sauna + Red Light → 00:34:21 - Alcohol + Hangovers → 00:35:18 - Exercise Performance + Recovery → 00:39:12 - Joint Pain + Osteoporosis → 00:42:16 - Middle Age Mental Health → 00:46:54 - Antimicrobials + Gut → 00:49:13 - Metabolic Health → 00:57:30 - The Gut Barrier → 01:00:12 - Impacts of Microplastics → 01:05:07 - Microplastic Detox → 01:07:27 - Micropastic Study → 01:11:17 - Supplement Stacking → 01:12:10 - Skincare + Gut → 01:17:03 - Bacteria + Inflammation → 01:18:33 - Menopause Benefits Check Out Mara Labs: → For the next week, Dr Tyna Show loyal listeners can get an exclusive 25% off all Mara Labs products when you go to www.mara-labs.com/DRTYNA and use code DRTYNA at checkout. After May 7th, the code will return to the standard 15% off. Disclaimer: Information provided in this podcast is for informational purposes only. This information is NOT intended as a substitute for the advice provided by your physician or other healthcare professional, or any information contained on or in any product. Do not use the information provided in this podcast for diagnosing or treating a health problem or disease, or prescribing medication or other treatment. Always speak with your physician or other healthcare professional before taking any medication or nutritional, herbal or other supplement, or using any treatment for a health problem. Information provided in this blog/podcast and the use of any products or services related to this podcast by you does not create a doctor-patient relationship between you and Dr. Tyna Moore. Information and statements regarding dietary supplements have not been evaluated by the Food and Drug Administration and are not intended to diagnose, treat, cure, or prevent ANY disease.

Transcript

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0:00.0	Maybe people don't know this.
0:01.7	As you lose this estrogen receptor alpha activation,
0:06.0	you're losing a whole bunch of activities that are protected.
0:09.2	So if you have a head of broccoli,
0:10.1	start chewing it, the glucoraphne,
0:12.4	the precursor molecule is in there.
0:14.4	You break the cell wall through the chewing,
0:16.7	and it releases an enzyme that converts that
0:19.7	glucoraphne into into sulfurophane.
0:21.5	You swallow it, you get the benefit.
0:22.9	You are tuned into the Dr. Tina show with Dr. Tina Moore.
0:25.9	For more, visit Dr.tina.com.
0:29.8	David and John, thank you so much for coming on the Dr. Tina show today.
0:33.6	I'm really excited to have you here today.
0:35.2	We're going to tell a cool story that I think my
0:37.5	listeners need to hear about Sophorafane. And I found your product along the way. And we are
0:45.1	going to just jump in. And everybody listening, just hang in there. We're going to bring this
0:48.8	all together. So will you guys introduce yourselves and let the audience know a bit about you?
0:53.1	Yeah. First of all, thanks for having us.
0:55.0	I'm David Roberts, I'm one of the founders of Mora Labs,
0:58.0	and I have a background in public health and biomedical engineering.
1:02.0	Yeah, John Gilday.
	...

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