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Science Weekly

The babies born with DNA from three parents

Science Weekly

The Guardian

Science

4.2938 Ratings

🗓️ 22 July 2025

⏱️ 17 minutes

🧾️ Download transcript

Summary

Doctors in the UK have announced the birth of eight healthy babies after performing a groundbreaking procedure that creates IVF embryos with DNA from three people. Ian Sample tells Madeleine Finlay about the life-threatening genetic disorders that the technique appears to prevent, and Prof Sir Doug Turnbull describes the 25-year journey to achieving the breakthrough. Help support our independent journalism at theguardian.com/sciencepod

Transcript

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0:00.0

This is The Guardian.

0:11.3

Last week, scientists announced an incredible medical advance.

0:16.8

Eight babies have been born here in the UK thanks to a groundbreaking IVF technique which uses genetic material from three people.

0:23.6

The pioneering procedure was developed to prevent mitochondrial diseases, which can be extremely serious and often fatal, being passed from mother to child.

0:34.6

If you've got a child with mitochondrial disease,

0:40.4

it has huge impacts on the whole family.

0:42.3

And I don't think that can be underestimated.

0:45.3

The treatment at the moment is treating symptoms.

0:49.7

For now, mitochondrial diseases remain incurable.

0:52.5

Some women decide to be childless.

0:54.0

Some people will adopt. Some people were considered egg donation.

0:56.5

But for the women that we're talking about, there wasn't any other option apart from rolling the dice and hoping that somehow they were lucky.

1:05.2

But that's an awful thing to do when you're thinking that you're talking about the life of a child.

1:10.5

But this groundbreaking new technique offers hope to prospective parents

1:15.5

that they can have healthy babies and the families they'd always wanted.

1:21.3

From The Guardian, I'm Madeleine Finley, and this is Science Weekly.

1:30.4

Ian Sampal, thanks again for joining me.

1:33.4

Now, last week you covered this quite incredible story

1:36.8

that eight healthy babies had been born

1:39.6

via this technique that's been developed by scientists

1:43.6

to prevent or reduce the risk of mitochondrial

1:47.2

diseases. And as part of this, you spoke to one of the scientists involved, who we will be hearing

...

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