5 • 716 Ratings
🗓️ 19 November 2020
⏱️ 11 minutes
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0:00.0 | Hey all, welcome back to the Real Life Pharmacology podcast. I'm your host, pharmacist Eric Christensen, |
0:06.1 | and I thank you so much for listening today. If you are looking for a free 31-page PDF, |
0:12.3 | definitely go check out real-life pharmacology.com. It's a top 200 study guide where I lay out the most important and relevant clinical pearls |
0:24.3 | as well as those things that come up on pharmacology exams on a regular basis there. |
0:31.3 | So definitely go take advantage of that free resource simply for subscribing. |
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0:52.9 | All right, so the drug of the day today is scopolamine and specifically transdermal scopolamine. |
0:55.2 | Now this is classified as an anticholonergic medication, and its primary use is the |
1:03.0 | prevention of nausean vomiting, and that could be due to a couple of reasons. |
1:08.9 | Most common reason I've seen this medication used in clinical practice |
1:13.6 | is for motion sickness, but it can also be used for nausea and vomiting associated with |
1:20.8 | anesthesia or general surgery. Now, how does this medication work? |
1:29.2 | Again, being an anticholinergic medication, it's going to block muscarinic receptors, possibly also has some an antihistamine-type activity, and it's going to block the action of acetylene, which can ultimately cause some drying up of secretions, |
1:52.0 | slow down the gut, and potentially provide some relief for nausea and vomiting, |
1:58.5 | which is what we're going to primarily use this medication for. |
2:05.1 | Adverse effect profile. So let's talk about this a little bit, because this gives me the |
2:11.3 | perfect example of explaining the prescribing cascade. |
2:18.8 | So adverse effects, knowing that it's an anti-colonergic medication, |
2:24.8 | what you're going to see is dry mouth, dry eyes, potentially constipation, |
2:30.0 | and urinary retention. |
2:32.9 | In addition, there might be some sedation, confusion, fall risk. |
2:38.8 | That's more so probably in our geriatric population. So let's talk about that prescribing cascade. |
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