5 • 716 Ratings
🗓️ 26 November 2020
⏱️ 13 minutes
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0:00.0 | Hey, all, welcome back to the Real Life Pharmacology podcast. |
0:03.8 | I'm your host, pharmacist Eric Christensen, and I thank you so much for listening. |
0:08.3 | If you'd like to track me down for comments, questions, anything there, |
0:12.2 | Eric Christensen, FarmD, B-CPS, B-C-GP on LinkedIn, that's probably the social media platform I'm most active on. |
0:21.3 | Or you can catch me at Med Education 101 at gmail.com. |
0:28.3 | And of course, I've got to remind you at real-life pharmacology.com. |
0:33.0 | We've got a free 31-page PDF on the top 200 drugs. |
0:38.3 | So it's a great little study guide where I lay out things that actually happen in clinical practice, |
0:43.3 | as well as things that frequently come up on pharmacology and or board exams. |
0:51.3 | So let's get into the medication I want to discuss today, and that is levateracetam. |
0:58.0 | Brand name of this medication is Kepra, and it can be used for seizure prophylaxis |
1:04.5 | and management of many different types of seizures in general. |
1:10.6 | Mechanistically, it's not actually really well understood how this medication works. |
1:19.7 | It's suspected it may have inhibitory action on voltage-gated calcium channels in the central nervous system. |
1:30.0 | And this may aid in promoting the action of GABA, which if you remember what GABA does, |
1:37.9 | it is an inhibitory type neurotransmitters. |
1:42.0 | So that's potentially, again, not totally well understood, |
1:46.6 | but potentially how it could help in managing seizure disorder. |
1:53.4 | Adverse effect profile, most common thing that I have seen in clinical practice by far is fatigue, potentially dizziness, |
2:06.2 | and then probably less common, you may see some psychiatric changes. |
2:11.5 | So whether that be agitation or anxiety, things like that. |
2:16.6 | Rare adverse effects, |
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