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Science Quickly

Salmonella Could Have Caused 16th-Century Epidemic

Science Quickly

Scientific American

Science

4.2639 Ratings

🗓️ 17 January 2018

⏱️ 3 minutes

🧾️ Download transcript

Summary

Using a new algorithm, geneticists uncovered the pathogen that could have caused a massive epidemic in the Aztec empire: Salmonella bacteria. Christopher Intagliata reports. Learn more about your ad choices. Visit megaphone.fm/adchoices

Transcript

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0:00.0

Understanding the human body is a team effort. That's where the Yachtel group comes in.

0:05.8

Researchers at Yachtolt have been delving into the secrets of probiotics for 90 years.

0:11.0

Yacold also partners with nature portfolio to advance gut microbiome science through the global grants for gut health, an investigator-led research program.

0:19.6

To learn more about Yachtolt, visit yawcult.co.

0:22.7

.jp.j. That's y-A-K-U-Lt.C-O.jp. When it comes to a guide for your gut, count on Yacolt.

0:33.6

This is Scientific American's 60-second science. I'm Christopher in Taliatta.

0:39.0

When Europeans arrived in the new world, they carried with them microscopic deadly organisms,

0:44.5

like smallpox, measles, and flu, which caused devastating outbreaks among the indigenous people.

0:50.5

One of those outbreaks was what became called the Koko-Litsli epidemic of 1545,

0:55.0

among the people known as the Mischtecs, in what is today southern Mexico.

1:00.0

The victims suffered rashes and fevers, blood streamed from their eyes, noses, and mouths.

1:05.0

Millions died. But we're still not sure what caused it.

1:09.0

So scientists looked to ten victims, buried in communal graves

1:12.6

in one of the afflicted towns for clues. They sequenced DNA from within their pulpy tooth

1:17.7

cavities. Most studies of ancient bones ditch all the associated microbial DNA so that only the host

1:23.6

DNA is analyzed. But in this case, the bacterial and viral DNA were the stars of the show,

1:29.0

which also meant a lot more genetic data to sift through. The difference is the needle in the haystack.

1:34.8

Noreen-2 Ross, a biochemist at Harvard University. This is a much bigger haystack. Using a new algorithm

1:40.7

to help him dive into that huge haystack, they found a needle.

1:50.0

Genetic evidence of the deadly salmonella enterica paratyphi C bacterium, which causes enteric fever. The results are in the journal Nature, Ecology, and Evolution.

1:55.1

The researchers stopped short of pinning the epidemic on the salmonella alone.

1:59.0

Could there have been other organs around?

...

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