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Real Life Pharmacology - Pharmacology Education for Health Care Professionals

Salmeterol (Serevent) Pharmacology

Real Life Pharmacology - Pharmacology Education for Health Care Professionals

Eric Christianson, PharmD; Pharmacology Expert and Clinical Pharmacist

Education, Health & Fitness, Medicine

5716 Ratings

🗓️ 21 April 2022

⏱️ 15 minutes

🧾️ Download transcript

Summary

In this episode, I cover salmeterol (Serevent) pharmacology, adverse effects, drug interactions and special warnings with this medication.



Salmeterol is a long acting beta agonist that can be used in combination with inhaled corticosteroids for management of asthma.



Salmeterol can be used as monotherapy in COPD and should not be used as monotherapy in asthma.



Elevations in pulse and blood pressure can happen with a beta agonist like salmeterol.

Transcript

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0:00.0

Hey, all, welcome back to the Real Life Pharmacology podcast. I'm your host, pharmacist, Eric Christensen.

0:05.3

Thank you so much for listening today. Go check out RealLife Pharmacology.com. Get your free 31-page

0:12.2

PDF. It's a study guide on the top 200 drugs. No brainer to have just simply an email. You'll get on our

0:19.4

email list. We'll shoot you messages when we've got new

0:22.9

podcasts out and new content available so again real life pharmacology dot com top 200 study guide go

0:29.4

snag that for free all right the drug of the day today is salmeterol brand name of this medication

0:36.0

is serivant note it is also contained within the product of

0:42.6

Advair, which is probably more commonly used, at least in my experience. So that's in combination with

0:48.9

an inhaled corticosteroid and solometerol there. So sommeterol is a long-acting beta-2 agonist. You'll see the acronym all

0:58.8

the time about laba therapy. So that stands for, again, long-acting beta-2 agonist. And with that,

1:08.6

it's an inhaled respiratory medication dry powder,

1:12.4

and it is used in the treatment of asthma and COPD.

1:18.4

Now, I do want to caution you the use in asthma.

1:23.2

So this drug cannot be used as monotherapy.

1:28.5

Okay, very, very important to remember that.

1:31.0

And there's actually boxed warnings due to an increased risk of death

1:36.2

when this drug, solmederal, is used as monotherapy.

1:40.7

Now, it obviously can be used in combination for the treatment of asthma when it is used with an inhaled corticosteroid.

1:51.5

And if you remember the asthma guidelines, when we need a controller medication, we generally start, or we do always start with an inhaled corticosteroid

2:03.9

taken on a daily basis if we're going to do maintenance therapy. And then we don't switch

2:10.9

if, you know, we still need more coverage. We add on therapy from there. So generally

2:16.5

inhaled corticosteroid, bump up the dose, and then if

...

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