S8 Ep491: Mary Roach details xenotransplantation and chimeras for organ replacement, while also recounting historical nasal reconstructions and the use of the Fibonacci sequence in modern plastic surgery techniques. 3
The John Batchelor Show
John Batchelor
4.5 • 2.8K Ratings
🗓️ 22 February 2026
⏱️ 14 minutes
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| 0:00.0 | This is CBSI in the world. I'm John Batchel with Gregory Zuckerman. His new book is A Shot |
| 0:09.5 | to Save the World, the inside story of the life or death race for a COVID-19 vaccine, |
| 0:14.4 | taking place over many decades, certainly here over all of the 21st century so far. the methodology of RNA, not proved yet, but it's |
| 0:24.4 | the methodology that modern is following. Now we go to a genius, a man who is gifted, enormously |
| 0:31.5 | gifted. His name is Dan Baruch. He is so gifted, his colleagues working with him at Beth Israel, Deaconess Medical Center, and elsewhere, come up with an adjective meaning Baruchian. |
| 0:44.3 | Your style is Baruchian. |
| 0:46.3 | Gregory, what do we need to know about Dan Baruch and how eventually he will come to Johnson and Johnson? |
| 0:52.8 | So we talked about MRNA, and there were people like Bancel and Moderna spending years working on that and improving that approach. |
| 0:59.8 | But there was another approach at the same time that other scientists around the world were trying to improve and hone. |
| 1:05.3 | And it was also controversial. |
| 1:06.8 | And that's what Dan Baruch was doing. |
| 1:08.4 | It was an approach using a virus, taking a virus and using it as a vaccine, as the basis of vaccine. |
| 1:15.0 | And what Dan Baruch did is use something called Ad26. |
| 1:18.5 | It's a harmless cold virus. |
| 1:20.4 | And you say, well, why would you inject a virus in your body to heal, to teach the body as part of a vaccine? |
| 1:29.5 | Well, they render, they may, |
| 1:36.4 | they change the composition, the chemical composition of this 26 virus, Baruch was able to make it harmless. So it's a harmless virus. And the idea being you're going to shepherd in a genetic |
| 1:41.9 | message. The virus is going to be injected in the body and it's going to |
| 1:46.8 | carry a message. And what's that message? It's going to tell the immune system to create a protein. |
| 1:51.3 | And he was focused on HIV. And the whole idea was to create a protein and HIV protein in the body. |
| 1:57.8 | And you saw it and say yourself, what's the point of that? Well, it's to teach |
| 2:01.7 | the immune system to identify that protein. And then if the body ever encounters that protein, |
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