Hey all, welcome back to the Real Life Pharmacology podcast. I am your host, pharmacist, Eric Christensen.

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All right.

So let's chat today about refaxamine.

So refaxamine is not a drug I see used on an everyday basis by any means.

The brand name of the medication is xifaxin.

And it is technically classified as a rithamysin antibiotic.

So if you remember from a previous podcast, I believe I've covered refampin in the past,

one of those drugs that's definitely very notorious for drug interactions.

I'll talk about that further in a little bit with refaxamine.

But refaxamine specifically is limited to the use basically of gut problems and gut infections.

So C. diff is a common infection that we use oral vancomycin,

oftentimes, but refaxamine is a potential alternative in the management of C. diff.

So again, probably not a first-line medication for C-DIF,

but certainly a viable option that can help manage that type of infection.

Probably the second most common situation I've seen this medication used is hepatic encephalopathy.

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