Naproxen Pharmacology
Real Life Pharmacology - Pharmacology Education for Health Care Professionals
Eric Christianson, PharmD; Pharmacology Expert and Clinical Pharmacist
4.9 • 773 Ratings
🗓️ 11 March 2021
⏱️ 13 minutes
🧾️ Download transcript
Summary
On this episode of the Real Life Pharmacology Podcast, I discuss naproxen pharmacology.
Naproxen can raise the concentrations of lithium and increase the risk for toxicity.
Compared to most other NSAIDs, naproxen tends to have a lower cardiovascular risk.
Naproxen can contribute to renal insufficiency, GI bleed risk, and CHF exacerbations.
I discuss important drug interactions on the podcast, be sure to check out my latest project which is a 200+ page book on managing drug interactions in primary care.
Be sure to check out our free Top 200 study guide – a 31 page PDF that is yours for FREE!
Transcript
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| 0:00.0 | Hey, all, welcome back to the Real Life Pharmacology podcast. |
| 0:03.7 | I'm your host, pharmacist Eric Christensen, and I thank you so much for listening today. |
| 0:08.7 | Today, I'm going to cover naproxin. |
| 0:13.2 | Brand name of this medication is Naprosin. |
| 0:16.6 | I probably most commonly hear patients call naproxin Aleve is another brand name that goes with it as well. |
| 0:26.6 | As full disclosure, I have talked about ibuprofen in the past, as well as the entire class of ENSED. |
| 0:36.2 | So there's some of the information here that is similar to that. |
| 0:41.3 | But I did want to talk about some specifics |
| 0:43.5 | that I think are really important with naproxin as well. |
| 0:48.5 | So first off, what is naproxin? |
| 0:51.1 | It is an N-SED, non-stroidal. |
| 0:53.7 | You'll often hear it referred to as kind of shorthand. |
| 0:58.3 | And it is used primarily for anti-inflammatory, pain syndromes, fever potentially. |
| 1:07.9 | And those are really the big three. And it is available over the counter. So that presents |
| 1:14.4 | some challenges as a provider, as a pharmacist, as a nurse. You've got to recognize that people |
| 1:22.5 | pick up these medications on their own and they start taking them and they often don't report it to a health care professional. |
| 1:31.3 | Okay, so I can't stress it enough. You've got to get medication lists updated and you've got to ask patients whether they're taking over-the-counter medications and try to get that teased out because it certainly does happen. |
| 1:48.3 | There is variations, and I think I might have forgot to mention it with the ibuprofen podcast, |
| 1:55.8 | but there is variations with these medications and over-the-counter composition. So you've got something like |
| 2:04.4 | Advil PM or Aleve PM. This is going to have an additional medication in it. And it's usually |
| 2:11.2 | an older anticholinergic sedative type medication because it's supposed to help with sleep as well. |
| 2:20.2 | Oftentimes it's diphenhydramine, |
... |
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