RHR: Beyond the Gut: The Microbiome’s Role in Sleep, Energy, and Longevity, with Dr. Zain Kassam
Revolution Health Radio
Chris Kresser
4.7 • 1.7K Ratings
🗓️ 10 March 2026
⏱️ 45 minutes
🧾️ Download transcript
Summary
In this episode of Revolution Health Radio, Chris sits down with gastroenterologist and microbiome researcher Dr. Zain Kassam to explore the rapidly evolving science of the microbiome and its profound impact on sleep, circadian rhythm, cognitive performance, stress resilience, immune balance, and longevity. From groundbreaking research on microbiome diversity and sleep quality to emerging innovations like cobiotics, Dr. Kassam explains how our microbial partners regulate core biological systems far beyond the gut. They discuss the connection between the gut and the brain, eyes, skin, and even ears—along with practical strategies for supporting microbial health in a modern world that constantly disrupts it.
The post RHR: Beyond the Gut: The Microbiome’s Role in Sleep, Energy, and Longevity, with Dr. Zain Kassam appeared first on Chris Kresser.
Transcript
Click on a timestamp to play from that location
| 0:00.0 | Chronic stress and poor sleep are at the root of so many health issues. |
| 0:14.0 | But between work deadlines, family responsibilities, and everything else life throws at us, |
| 0:18.9 | finding calm can feel impossible. |
| 0:22.4 | That's why I formulated steady spirit, a comprehensive stress and mood support supplement from my Adapt Naturals line. It features |
| 0:29.0 | clinically backed doses of five powerhouse ingredients like Afron-Safron, Sensero Aschaganda, |
| 0:35.8 | Rilissa Lemonbaum, Elthianine, and Holy Basel to help you manage everyday stress, |
| 0:41.0 | promote a sense of calm, achieve focus clarity during the day, and support better sleep at night. |
| 0:47.3 | Just two capsules a day deliver real results. Reduce stress, a calmer mind, improve mood, |
| 0:53.0 | better focus without jitters, and more restful sleep, |
| 0:56.4 | with noticeable benefits in as little as two weeks. Visit adapt naturals.com to learn more about |
| 1:02.3 | steady spirit and take the first step toward going from wired and tired to calm and clear, |
| 1:07.2 | naturally from the inside out. Hey everybody, Chris Kresser here. |
| 1:11.5 | Welcome to another episode of Revolution Health Radio. |
| 1:14.6 | This week I'm really excited to welcome Dr. Zane Kasam as my guest. |
| 1:18.9 | He is an award-winning physician scientist, a gastroenterologist who has shaped the field of microbiome |
| 1:24.3 | science for more than a decade, authored over 200 peer-reviewed publications |
| 1:28.3 | and abstracts and co-authored international clinical practice guidelines. He is an expert in the |
| 1:36.3 | microbiome and its relationship to all aspects of health and well-being. This is a fascinating topic |
| 1:42.8 | that has evolved so much in my 20 years as a clinician, |
| 1:47.0 | researcher, and educator. In the early days, we thought that the microbiome was mostly just |
| 1:53.6 | about digestive health, and all you needed to do was maybe eat some fermented food and take a probiotic, |
| 1:59.2 | and you're good to go. And we know now that it's so |
... |
Please login to see the full transcript.
Disclaimer: The podcast and artwork embedded on this page are from Chris Kresser, and are the property of its owner and not affiliated with or endorsed by Tapesearch.
Generated transcripts are the property of Chris Kresser and are distributed freely under the Fair Use doctrine. Transcripts generated by Tapesearch are not guaranteed to be accurate.
Copyright © Tapesearch 2026.