Rewiring Your Brain to Utilize Dopamine | Andrew Huberman
The Daily Motivation
Lewis Howes
4.8 • 960 Ratings
🗓️ 3 February 2026
⏱️ 7 minutes
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| 0:00.0 | Hi, my name is Lewis Howes and welcome to the Daily Motivation Show. |
| 0:12.4 | Pursuit is very taxing. And the reason is that there's a biochemical reason for this is |
| 0:17.1 | it's like wandering in the desert, not knowing if there's water at all that's really |
| 0:21.5 | depleting i mean epinephrine is in the brain and it's a it's chemical equivalent in the body is |
| 0:27.1 | adrenaline those are the same thing and if you're constantly in pursuit right you're just pursuing |
| 0:33.2 | external goals external goals external goals it will wear your nervous system down. You will be exhausted and |
| 0:38.7 | one will eventually run aground. You'll become mentally depressed. The key is to figure out what are |
| 0:44.9 | the rewards that you can acquire along the way internally. Remember, it's subjective. There can also be |
| 0:50.8 | external rewards because many things have milestones, you know, a series A or a series B for a company, then the IPO later. |
| 0:57.0 | Reaching a million users or doing this, yeah. |
| 0:59.0 | We have engagements before we have weddings typically, right? |
| 1:02.0 | There's a lot of buildup that fortunately, you know, provides these reward mechanisms. |
| 1:08.0 | So the key thing is that you can't just be all gas pedal all the time without |
| 1:15.5 | rewarding yourself. However, the reward that dopamine is so powerful because it actually is the |
| 1:21.9 | chemical substrate for epinephrine. It creates a reservoir of more energy. And again, I'm not talking about caloric energy or |
| 1:29.5 | glycogen. It's mental energy. It's the desire to push on. It's the desire to keep going. So we need some |
| 1:36.4 | consistent dopamine hits throughout the days or our months to give us more energy to pursue. |
| 1:42.0 | That's right. But we don't want to be over pursued because then we'll burn out. That's right. And so everyone has to find where that sweet spot is that kind of, you know, on the freeway driving where it's really smooth and seamless, where you're not on the accelerator the whole time, where you're in a gear that's appropriate. You know, we're talking now in terms of sort of neuroscience lens on these |
| 2:02.5 | things, but the key is always going to be practices. It's going to be just as earlier we're |
| 2:06.9 | talking about bringing stress levels up or down, depending on, you know, alertness levels up |
| 2:11.8 | or down, depending on the kind of stress you're experiencing. Let's say you're a person that can |
| 2:16.7 | very easily access this dopamine reward. So you're always excited. You know,'re a person that can very easily access this dopamine |
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