Rewiring an Addicted Brain | Deborah Mash

The Lindsey Elmore Show

Lindsey Elmore

Health & Fitness, Nutrition, Alternative Health, Medicine

5.0 • 529 Ratings

🗓️ 17 January 2023

⏱️ 58 minutes

🔗️ Recording | iTunes | RSS

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Summary

Deborah Mash is neuroscientist, inventor and one of the world's foremost experts on the hallucinogenic drug ibogaine. She is the CEO and Founder of DemeRx Inc., a clinical stage drug development company advancing ibogaine and its active metabolite noribogaine for the treatment of opioid use disorder. DemeRx has partnered with ATAI Life Sciences -- a global biotech platform with a special focus on psychedelic medicine -- to develop ibogaine for those suffering from opioid use disorder. Building on the extensive human data available around ibogaine, DemeRx and ATAI will submit Clinical Trial Applications for a Phase II study in opioid-dependent patients to address the current opioid crisis in America. Deborah Mash is Professor of Neurology (Emeritus) and Molecular and Cellular Pharmacology at the University of Miami Miller School of Medicine. She has held uninterrupted NIH funding from the National Institute on Drug Abuse for over thirty years. She works with a team of scientists, clinicians and other researchers and entrepreneurs to bring discoveries to patients. Topics covered in this episode: Discoveries of the Brain Hallucinogenic Research Ibogaine Metabolites Withdrawls Pharmacology Rewiring the Brain Alkaloids in Plants Psychiatry & Psychedelics Referenced in the episode: The Lindsey Elmore Show Ep 202 | Drunk: Why We Drink and How It Civilized Us | Edward Slingerland To learn more about Deborah Mash and her work, head over to https://www.demerx.com/ __________________________________________________________ This is the perfect time to assess your current routines. What is serving you, what isn't, and is there anything that can help aid your health and wellness journey. This is where Sambucol comes in. They help support a healthy immune system so that you can keep moving, helping your daily dose of black elderberry to happen with ease. With a wide variety of products, Sambucol will pump up that immunity so that it can keep you moving. Listeners of Lindsey Elmore can get 15% off of $9.99 or more at www.SambucolUSA.com by using my promo code Lindsey15 at checkout! __________________________________________________________ Do you want to live a healthy lifestyle but you don’t know where to find reliable health education, you don’t have someone you can trust to lead you to which health and wellness options are out there. When you go to http://www.Wellnessmadesimple.us you can learn practical skills that you need to build a healthy lifestyle. You’ll gain access to more than 85 videos, 11 hours of education and more education is always being added, and you'll join a community that has given more than 2400 positive reviews. All you have to do is get access, and right now we are offering half off of an annual subscription when you shop the code 2023Wellness and after that, watch the coursework, then implement daily changes positively transform your help you can feel better. Go to http://www.Wellnessmadesimple.us to get an annual subscription, and shop the code 2023Wellness for half off of your annual subscription. __________________________________________________________ __________________________________________________________ We hope you enjoyed this episode. Come check us out at www.lindseyelmore.com/podcast.

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Transcript

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0:00.0	More people in the United States each year die from prescription opioid abuse than from heroin and cocaine combined.
0:08.1	Methadone and buprenorphine are opioid substitution therapies that currently dominate the addiction treatment market.
0:15.0	But these medications don't actually treat the addiction.
0:18.6	They still are opiates and they are used to help
0:22.8	interrupt the pattern of addictive behavior that goes along with searching out prescription opioids.
0:32.1	Patients need to have access to safe and effective treatment that actually breaks the cycle of something that can feel
0:39.7	intractable the abuse the dependence the seeking and all of the ongoing withdrawal
0:47.4	today I am going to be talking with dr. Deborah mash about how psychedelic medicines can help to break the cycle of addiction.
0:57.3	We also talk about how we can use psychedelic therapies for the treatment of addictions and how we can
1:04.3	do it using clinically backed research as well as safe and best practices to ensure that the use of the psychedelic is both safe
1:14.8	and efficacious. This is the Lindsay Elmore Show. Welcome to the Lindsay Elmore Show, a podcast
1:23.7	for people who deserve to be healthy with honest, open, and enlightening conversations with doctors, thought leaders,
1:31.7	creatives, and spiritual gurus, you'll walk away with simple and tangible tips and tricks
1:38.5	that allow you to live your healthiest life so you can pursue your dreams,
1:46.6	overcome obstacles, and leave your mark.
1:56.3	Deborah Mash is a neuroscientist inventor and one of the world's foremost experts on the hallucinogenic drug Ibogaine. She is the CEO and founder of DemiRX, a clinical stage drug development company advancing Ibegain and its active metabolite, Noribagane, for the treatment of opioid use disorder.
2:11.9	DemirX has partnered with Atai Life Sciences, a global biotech platform with a special focus on psychedelic medicine,
2:21.2	to develop Ibogaine for those suffering from opiate use disorder. Building on the extensive
2:27.9	human data available around the world on Ibogaine, Demirx and a tie will submit clinical trial applications for
2:36.7	phase two study in opioid dependent patients to address the current opioid crisis in America.
2:44.5	She is a professor emeritus of neurology and molecular and cellular pharmacology at the University of Miami Miller School
2:53.0	of Medicine. She has held uninterrupted NIH funding from the National Institute on Drug Abuse
	...

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