PT500 – Shulgin Farm and the Future of Psychedelic Drug Development, with Paul F. Daley, Ph.D.
Psychedelics Today
Psychedelics Today, LLC
4.6 • 598 Ratings
🗓️ 2 April 2024
⏱️ 36 minutes
🧾️ Download transcript
Summary
In this episode, Joe interviews Paul F. Daley, Ph.D., who worked with Sasha Shulgin in his lab for the last seven years of his life, helping him finish (and co-authoring) "The Shulgin Index, Volume One: Psychedelic Phenethylamines and Related Compounds."
He is now the co-founder, Chief Science Officer, and Director of Analytical Science at the Alexander Shulgin Research Institute (ASRI), focusing on the discovery and development of novel psychedelic compounds. While Sasha was passionate about self-experimentation, the Institute is aiming for the next step for these drugs: FDA approval.
He discusses:
- Meeting Sasha at the 2nd international conference on hallucinogenic mushrooms in Washington D.C.
- Bonding with Sasha while reviewing the autopsy of researcher Robert van den Bosch for possible foul play
- The two compounds ASRI is closest to being able to test in clinical trials
- The 5-HT2B receptor, risk of valvular disease, and why we will likely be hearing more about this going forward
- How AI and new technology can lead to better safety science
and more!
Click here to head to the show notes page.
Transcript
Click on a timestamp to play from that location
| 0:00.0 | Hi everybody. |
| 0:12.0 | Welcome back to Sagittalex today. |
| 0:14.0 | This is Joe Moore coming out from Bracken Ridge, Colorado. |
| 0:16.0 | Today on this show we have Paul Daly. |
| 0:19.0 | Paul Daly was working with Sasha Shoggan for years in his lab. |
| 0:24.8 | Paul is a very interesting guy and we got to record thanks to the Shulgin Foundation at the Shulgan |
| 0:32.0 | farm in Sasha's office which was amazing for me and in some cases made for some really great videos. So check out what we've done in partnership with our friends over at a hover. |
| 0:43.3 | Really epic videos on our YouTube. Honestly, so please do check those out. It's super cool. And yeah, Paul is also heading up the Shulgen Research Institute where they are actually doing the Shulgin process, you know, developing new molecules and trying to bring them across through a normal FDA route. |
| 1:06.4 | So slightly different from what we would see Sasha doing, which is testing on himself and testing |
| 1:12.8 | with some others, reporting the results. But I think it's important. There's a lot of molecules |
| 1:17.7 | that definitely do need to make it into the pharmacopia. And I think the name of the group |
| 1:25.3 | is the Alexander Shulkin Research Institute, ASRI, |
| 1:30.4 | psychedelic discovery development. |
| 1:32.7 | And yeah, it's great. |
| 1:35.3 | So thank you to our friends at Hover. |
| 1:37.6 | Ethan was there making some epic video for us. |
| 1:40.0 | And then the Shulgin Foundation for making these interview slots available for us. |
| 1:45.4 | I really appreciated it. |
| 1:47.2 | And thanks to Paul for sitting down with me as well. |
| 1:50.2 | Really lovely. |
| 1:51.4 | So I think that's it for now. |
| 1:53.6 | So thank you all for tuning in. |
... |
Please login to see the full transcript.
Disclaimer: The podcast and artwork embedded on this page are from Psychedelics Today, LLC, and are the property of its owner and not affiliated with or endorsed by Tapesearch.
Generated transcripts are the property of Psychedelics Today, LLC and are distributed freely under the Fair Use doctrine. Transcripts generated by Tapesearch are not guaranteed to be accurate.
Copyright © Tapesearch 2026.