Protect your liver and promote optimal metabolic health | Alan Flanagan, PhD

The Proof with Simon Hill

Simon Hill

Nutrition, Health & Fitness, Self-improvement, Education

4.9 • 2.9K Ratings

🗓️ 2 October 2023

⏱️ 144 minutes

🔗️ Recording | iTunes | RSS

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Summary

Episode #281. With nearly a quarter of the world's population estimated to be affected by non-alcoholic fatty liver disease (NAFLD), understanding its intricacies is crucial. Join me as Dr Alan Flanagan helps unravel the complexities of NAFLD, breaks down its wider health ramifications, and offers insights on managing and living with the condition. We discuss: Introduction to Fatty Liver Disease (00:00) Understanding Non-Alcoholic Fatty Liver Disease and Its Development (02:27) Risk Factors: Gender Differences in Fatty Liver Disease Development (09:33) The Science of Hepatic Fat Oxidation (14:45) Consequences and Effects of Fatty Liver Disease (20:25) Identifying Symptoms of Non-Alcoholic Fatty Liver Disease (25:54) Risk Assessment: Non-Alcoholic Fatty Liver Disease in Premenopausal Women (29:33) Energy Toxicity and Misconceptions about BMI (34:50) Linking Non-Alcoholic Fatty Liver Disease with Type 2 Diabetes (48:34) Liver Changes During Non-Alcoholic Fatty Liver Disease Progression (1:02:16) Strategies for Reducing Fat Accumulation in the Liver (1:05:28) The Role of Time-Restricted Eating in Managing Fatty Liver Disease (1:11:41) The Impact of Sugars on Fatty Liver Disease (1:20:16) Understanding the Relationship Between Dietary Fats and Fatty Liver Disease (1:41:16) High Saturated Fat Diets and Their Effect on Fatty Liver Disease (1:57:19) Importance of Caloric Source Variation in Dietary Fats (1:59:23) Beneficial Dietary Patterns for Liver Health (2:04:07) Analysing Dairy Types and Their Effects on Liver Fat (2:08:29) Meal Frequency and Its Relation to Liver Fat Accumulation (2:12:40) Recommended Lifestyle Changes for Preventing Non-Alcoholic Fatty Liver Disease (2:17:59) Conclusion: Key Takeaways on Fatty Liver Disease Management (2:20:07) Connect with Alan Flanagan on Instagram, and learn more about his company, Alinea Nutrition, here. Make sure to listen to his five previous appearances on The Proof here. Optimise your health with InsideTracker’s biomarker analysis. Get exclusive access to InsideTracker’s new ApoB test, and a significant discount at insidetracker.com/simon. Enjoy, friends. Simon Want to support the show? The best way to support the show is to use the products and services offered by our sponsors. To check them out, and enjoy great savings, visit theproof.com/friends. You can also show your support by leaving a review on the Apple Podcast app and/or sharing your favourite episodes with your friends and family. Simon Hill, MSc, BSc (Hons) Creator of theproof.com and host of The Proof with Simon Hill Author of The Proof is in the Plants Watch the episodes on YouTube or listen on Apple/Spotify Connect with me on Instagram, Twitter, and Facebook Nourish your gut with my Plant-Based Ferments Guide Download my complimentary Two-Week Meal Plan and high protein Plant Performance recipe book

Transcript

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0:00.0	Finally, it's here, the Essential Prenatal Supplement by Emil.
0:09.3	I've been waiting for a prenatal supplement for pregnant women that's properly formulated
0:14.3	with the right ingredients and dosages for a long time.
0:18.6	Essential prenatal contains DHA, an important omega-3 during pregnancy, colon, vitamin B-12,
0:25.6	and other important nutrients in optimal dosages for pregnant women following a plant
0:30.6	predominant or exclusive diet. Formulated by myself alongside previous show guest Dr.
0:36.1	German Newman, nutritionist Jacqueline Orwell, and naturopath Dr. Julie Chen.
0:41.8	Pregnancy is an extremely important life stage, certainly a time to make sure that you're not
0:47.9	falling short in your consumption of any critical nutrients. To learn more about essential prenatal
0:54.0	and get 10% off your first order, head to theproof.com forward slash friends. That's theproof.com
1:01.3	forward slash friends and follow the link to Emil's website.
1:08.2	Current estimates in terms of global estimates suggest give or take around 25% of the population
1:16.3	may exhibit fatty liver. The evidence is pretty clear that the primary driver of the net
1:25.1	accumulation of fatty liver is energy excess, chronic energy excess. If the liver becomes fatty,
1:32.6	the liver becomes insulin resistance. So you've got elevated glucose factors or hyperglycemic
1:38.2	factors. You've got elevated insulin factors and elevated insulin resistance in the liver,
1:46.3	all complicated by fatty liver. You've got this relationship with circulating lipids,
1:53.3	non-asteroid or free fatty acids, and elevated triglystides, all kind of interacting where the
2:01.5	presence of fatty liver can drive the progression of type to diabetes.
2:06.0	In today's conversation, Dr. Alan Flanagan returns to talk to us about non-alcoholic fatty liver
2:12.8	disease. In this episode, you will learn what non-alcoholic fatty liver disease is, who and how many
2:18.5	people this condition affects, how our liver is involved in metabolic health, how we can optimize
	...

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