meta_pixel
Tapesearch Logo
Log in
Real Life Pharmacology - Pharmacology Education for Health Care Professionals

Propylthiouracil Pharmacology Podcast

Real Life Pharmacology - Pharmacology Education for Health Care Professionals

Eric Christianson, PharmD; Pharmacology Expert and Clinical Pharmacist

Education, Health & Fitness, Medicine

4.9773 Ratings

🗓️ 15 December 2022

⏱️ 12 minutes

🧾️ Download transcript

Summary

In this podcast episode, I cover propylthiouracil pharmacology, adverse effect, drug interaction, and much more!

Propylthiouracil carries a boxed warning for hepatotoxicity which is a significant downside compared to the other agent in its class (methimazole).

What about dosing? I discuss why this medication has to be dosed multiple times per day.

Drug interactions aren’t incredibly common with propylthiouracil but it can affect warfarin differently than most drug interactions. I discuss it further in this episode.

Be sure to check out our free Top 200 study guide – a 31 page PDF that is yours for FREE!

Support The Podcast and Check Out These Amazing Resources!

NAPLEX Study Materials

BCPS Study Materials

BCACP Study Materials

BCGP Study Materials

BCMTMS Study Materials

Meded101 Guide to Nursing Pharmacology (Amazon Highly Rated)

Guide to Drug Food Interactions (Amazon Best Seller)

Pharmacy Technician Study Guide by Meded101

Transcript

Click on a timestamp to play from that location

0:00.0

Hey all, welcome back to the Real Life Pharmacology podcast. I'm your host, pharmacist, Eric Christensen.

0:06.1

As always, go check out Real Life Pharmacology.com. We've got the free Top 200 study guide.

0:14.3

Great no-brainer to have if you're in pharmacology classes, taking board exams, or if you're just looking for a refresher.

0:21.3

So again, real-life pharmacology.com will have that.

0:25.2

Simply an email will get you access.

0:27.6

All right, the drug of the day today is propyl thio-eurosome.

0:33.3

Now, most of you, if you've heard of this drug, have probably heard it referred by its name PtU,

0:40.9

or the abbreviation PtU.

0:43.5

Brand names of this medication, halosil, and thyracill or two that I've heard.

0:50.1

But overwhelmingly, I've heard folks call it PtU.

0:54.2

So that's probably what you'll hear in your pharmacology classes

0:58.2

and or clinical practice depending upon where you're at.

1:02.8

So this medication is an antithyroid agent.

1:07.3

So, you know, in a broad scheme of things, think the opposite of levo thyroxin,

1:13.9

which is basically supplementing or adding thyroid hormone. So as you could expect,

1:20.4

if it's an antithyroid agent, it's going to be used to manage hyperthyroidism. Graves disease

1:26.4

being kind of a classic example here. Now keep in mind there

1:31.2

are other medical procedures and things we do to manage hyperthyroidism. So medication therapy

1:37.2

like propylophtyotio or so may not be used in that situation. However, it is an option if patients are unable to do the other procedures,

1:46.6

that type of thing, which I'm not going to go into too much detail here. I want to focus on the drug,

1:51.6

but keep in mind that that is certainly an option as well, depending upon the diagnosis and the

1:59.0

situation that we're in.

...

Please login to see the full transcript.

Disclaimer: The podcast and artwork embedded on this page are from Eric Christianson, PharmD; Pharmacology Expert and Clinical Pharmacist, and are the property of its owner and not affiliated with or endorsed by Tapesearch.

Generated transcripts are the property of Eric Christianson, PharmD; Pharmacology Expert and Clinical Pharmacist and are distributed freely under the Fair Use doctrine. Transcripts generated by Tapesearch are not guaranteed to be accurate.

Copyright © Tapesearch 2026.