Hey all, welcome back to the Real Life Pharmacology podcast. I'm your host, pharmacist, Eric Christensen.

Thank you so much for listening today. As always, head on over to real life pharmacology.com.

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All right, the drug of the day today is minus cycling.

Brand name of this medication is minison. Mechanistically, and from a category standpoint, I guess,

this drug is an antibiotic, and it is a tetracycline derivative, as you could anticipate with the ending of the name.

Mechanistically, how to tetracycline's work, they, from a broad perspective, they block

bacterial protein synthesis. They do this by binding to the 30s and potentially to some extent the 50s ribosomal subunits

to prevent that bacterial protein synthesis. Definitely a question I've seen come up on board

exams and pharmacology exams throughout my career for sure.

So knowing that it's a tetracycline derivative, going to be in the same category as doxycycline,

tetracycline.

Usual dosing is similar to doxycline, and that is twice daily, 50 to 100 milligrams twice daily in most situations.

Now uses. The tetracyclines in general are a pretty broad spectrum antibiotic, and we do have IV and oral drug formulations. So skin and soft

tissue infections. And it even has coverage for community acquired MRSA. Acne. This is probably

where I see it used most often on a chronic basis,

kind of preventing and reducing the severity of acne.

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